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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

Research Article

Synthesis of Stable Isotope Labeled D5-Cyhalothrin, D5-Fenpropathrin and D5-Fenvalerate from Deuterium Phenol

Author(s): Zhongjie Xu, Shaofei Bai, Liyan Shen, Yong Luo* and Zuming Hu*

Volume 19, Issue 6, 2022

Published on: 10 June, 2021

Page: [453 - 456] Pages: 4

DOI: 10.2174/1570178618666210610170638

Price: $65

Abstract

A convenient synthetic route of deuterium-labeled D5-cyhalothrin, D5-fenpropathrin, and D5-fenvalerate is described with 98.7%, 98.5%, and 98.3% isotopic enrichment and high chemical purities using D6-phenol as labeled starting material. These structures and isotope-abundance were confirmed by 1H NMR and mass spectrometry. The prepared D5-cyhalothrin, D5-fenpropathrin, and D5- fenvalerate can be used as a standard internal reagent for the determination of residual pyrethroids of food and environment.

Keywords: D5-cyhalothrin, D5-fenpropathrin, D5-fenvalerate, isotopic abundance, food safety, standard internal reagent.

Graphical Abstract
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