Abstract
Hydrogels are hydrophilic but water-soluble polymer systems with a three-dimensional network structure. They can absorb large amounts of water and maintain their shape and remain soft. The high-moisturizing properties, good biocompatibility, and controlled biodegradability of hydrogels have allowed them to be widely used in wound dressing, tissue engineering, controlled drug delivery systems, and other fields. This article reviews the most widely used antibacterial gel dressings for wound healing in recent years and focuses on the application of an environmentally responsive intelligent hydrogel delivery system. Finally, the development prospects and challenges of hydrogel wound dressings are forecasted.
Keywords: Bioactive hydrogel, antibacterial hydrogel, wound healing, environmentally responsive hydrogel, drug delivery system, tissue engineering.
Current Medicinal Chemistry
Title:Insight Into Bioactive Hydrogels for Wound Healing and Drug Delivery Systems
Volume: 28 Issue: 42
Author(s): Jing Li, Qinhua Chen, Jin Wang, Xiaoyan Pan and Jie Zhang*
Affiliation:
- School of Pharmacy, Health Science Center, Xi'an Jiaotong University, Xi’an 710061, China
Keywords: Bioactive hydrogel, antibacterial hydrogel, wound healing, environmentally responsive hydrogel, drug delivery system, tissue engineering.
Abstract: Hydrogels are hydrophilic but water-soluble polymer systems with a three-dimensional network structure. They can absorb large amounts of water and maintain their shape and remain soft. The high-moisturizing properties, good biocompatibility, and controlled biodegradability of hydrogels have allowed them to be widely used in wound dressing, tissue engineering, controlled drug delivery systems, and other fields. This article reviews the most widely used antibacterial gel dressings for wound healing in recent years and focuses on the application of an environmentally responsive intelligent hydrogel delivery system. Finally, the development prospects and challenges of hydrogel wound dressings are forecasted.
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Cite this article as:
Li Jing , Chen Qinhua , Wang Jin , Pan Xiaoyan and Zhang Jie *, Insight Into Bioactive Hydrogels for Wound Healing and Drug Delivery Systems, Current Medicinal Chemistry 2021; 28 (42) . https://dx.doi.org/10.2174/0929867328666210405125348
DOI https://dx.doi.org/10.2174/0929867328666210405125348 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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