SARS-CoV-2: An Insight into Detection Tools

Title:SARS-CoV-2: An Insight into Detection Tools

Volume: 21 Issue: 8

Author(s): Shaghayegh Khanmohammadi, Mohammadreza Tabary, Farnaz Araghi and Seyed Mohammad Tavangar*

Affiliation:

• Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Tehran,Iran

Keywords: COVID-19, SARS-CoV-2, Diagnosis, Polymerase chain reaction, Computed tomography, Serology.

Abstract: The novel coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), was announced as a pandemic in March 2020. Different diagnostic laboratory tests have been used to detect the infection. Each diagnostic tool, such as Chest Computed tomography (CT) imaging, genome sequencing, nucleic acid amplification methods, whole genome sequencing, microarray, and serology testing have several advantages and disadvantages. Nucleic acid amplification methods are better diagnostic tools for the detection of SARS-CoV-2 in early stages of the infection, while serological tests are more appropriate for the recognition of previously infected patients. In this review, we will briefly consider each diagnostic method, and discuss its pros and cons.

Cite this article as:

Khanmohammadi Shaghayegh , Tabary Mohammadreza, Araghi Farnaz and Tavangar Mohammad Seyed *, SARS-CoV-2: An Insight into Detection Tools, Infectious Disorders - Drug Targets 2021; 21 (8) : e160921189885 . https://dx.doi.org/10.2174/1871526520666210104151849