Background: H1N1 is known to cause periodic seasonal flu in the Indian subcontinent since 2009. The clinical
course and the underlying
immunity of the host contribute to the development of secondary bacterial infections in the
Objectives: This study aims at analyzing the secondary bacterial infections in confirmed H1N1 cases admitted in our
hospital (from 2015 to 2018) with respect to the comorbidities, complications, associated bacteria with its antibiotic
susceptibility pattern and the outcome of such episodes.
Material and methods: Data of 164 patients admitted in a tertiary care hospital with H1N1 was extracted from medical
records using a semi-structured case report form. Data was entered
and analyzed with SPSS version 17. A p value of <0.05
was considered as statistically significant.
Results: Most patients were aged above 40 years with female preponderance. In our study 42% of patients had
comorbidities. Only 14 (8.53%) had secondary bacterial infection confirmed by culture. Klebsiella pneumoniae and
Acinetobacter baumannii were the most common bacteria that were isolated. They were treated based on the culture reports.
There was no mortality in patients with secondary bacterial infection.
Conclusion: The early start of the antiviral agents and adherence to the antibiotic policy of the hospital contributed to lower
secondary bacterial infections and zero mortality.