The study investigated the levels of cytokines IL-8 and TNF-α in vaginal secretion in a group of female patients
with Helicobacter-associated acid-related diseases who were or were not treated with antibiotics against anti-Helicobacter
therapy. It turned out that the secretory cytokine (chemokine) IL-8 is dramatically increased in the vaginal mucosa in patients treated with antibiotics, specifically in post-menopause women. Thus, we conclude that helicobacter pylori eradication
treatment affects the immune status of the female genital tract.
Keywords: Local immunity, female genital tract, interleukin-8 (IL-8), tumor necrosis factor-alpha (TNF-α), Helicobacter
Pylori associated acid-related diseases, eradication lines.
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