A novel coronavirus termed nCoV-2019 caused an epidemic of acute respiratory syndrome in humans was first
detected in Wuhan, China, in December 2019. nCoV-2019 resulted in thousands of cases of lethal disease all around the
world. Unfortunately, there is no specific treatment yet so better understanding of the pathobiology of the disease can be
helpful. The renin–angiotensin system and their products has several important physiological actions, On the other hand,
this system involved in the pathogenesis of various diseases. In this context, this review article will briefly insights for understanding
the role of angiotensin-converting enzyme 2 (ACE2) receptor as a potential attractive target for nCoV-2019-
induced acute respiratory syndrome.