Background: Iron-folic acid supplementation is a central preventive measure for maternal
anemia, so considering the factors leading to or deterring from adherence is important. This review
aims to establish if there is a correlation between increasing maternal education and adherence
to iron-folic acid supplementation in Ethiopia.
Methods: An electronic database search was conducted using PubMed, Google Scholar, Cochrane
Library and African Journals Online. Joanna Briggs Institute Meta-Analysis of Statistical Assessment
and Review Instrument was used for quality appraisal of the included studies. The extracted
data were entered into Microsoft™ Excel sheet and exported to R-software version 3.6.1 for analysis.
Maternal education on adherence of iron-folic acid supplementation was analyzed and subgroup
analyses of difference between regions and time of study period were conducted.
Results: The online search yielded a total of 936 articles, and based on inclusion/exclusion criteria
nine were included in this study with a total of 3263 participants. Applying the random effect model,
the analysis revealed that the odds of prenatal adherence of iron-folic acid supplementation
were 2.89 times higher in mothers with secondary school education and above as compared to
those who had not received formal education.
Conclusion: This review identified that increased maternal education leads to improved adherence
of iron-folic acid supplementation amongst women across Ethiopia. This information may inform
efforts of government and non-government organizations to encourage maternal education in order
to sustained adherence of iron-folic acid supplementation. Further research is required in this critical
area at regional, national, and global levels.