An Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-ones by Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst

Title:An Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-ones by Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst

Volume: 18 Issue: 10

Author(s): K. Kalyani and Srinivasa Reddy Kallam*

Affiliation:

• Technology Development Centre, Custom Pharmaceutical Services, Dr. Reddy’s Laboratories Ltd, Hyderabad 500 049, Telangana,India

Keywords: 2-substituted quinazolin-4 (3H)-ones, wang resin-supported sulfonic acid, recyclable catalyst, isatoic anhydride, amidoxime, anti-bacterial.

Abstract: An efficient synthesis of 2-substituted Quinazolin-4(3H)-ones has been developed from isatoic anhydride with various amidoximes by using a recyclable polymer-supported sulphonic acid catalyst. Excellent functional group compatibility and high yields are the important features of this protocol.

Cite this article as:

Kalyani K. and Kallam Reddy Srinivasa*, An Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-ones by Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst, Letters in Organic Chemistry 2021; 18 (10) . https://dx.doi.org/10.2174/1570178617999201109203731