Title:Role of Novel Drug Delivery Systems in Coronavirus Disease-2019 (COVID-19): Time to Act Now
VOLUME: 18 ISSUE: 3
Author(s):Neeraj Mittal, Varun Garg, Sanjay Kumar Bhadada and O. P. Katare*
Affiliation:Department of Endocrinology, Postgraduate Institute of Medical Education &Research, Chandigarh-160012, Department of Medical Affairs, Cadila Healthcare Limited, Ahmedabad 382421, Gujarat, Department of Endocrinology, Postgraduate Institute of Medical Education &Research, Chandigarh-160012, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced, Studies, Panjab University, Chandigarh- 160014
Keywords:Anti-viral, COVID-19, nanoparticles, novel drug delivery system, repurposing, vaccine.
Abstract:The coronavirus disease 2019 (COVID-19) has found its roots from Wuhan (China).
COVID-19 is caused by a novel coronavirus SARS-CoV2, previously named as 2019-nCoV. It has
spread across the globe and was declared as a pandemic by the World health organization (WHO)
on 11th March, 2020. Currently, there is no standard drug or vaccine available for the treatment,
therefore, repurposing of existing drugs is the only solution. Novel drug delivery systems (NDDS)
will be boon for the repurposing of drugs. The role of various NDDS in repurposing of existing
drugs for the treatment of various viral diseases and their relevance in COVID-19 has been discussed
in this paper. It focuses on the currently ongoing research in the implementation of NDDS
in COVID-19. Moreover, it describes the role of NDDS in vaccine development for COVID-19.
This paper also emphasizes how NDDS will help to develop the improved delivery systems
(dosage forms) of existing therapeutic agents and also explore the new insights to find out the void
spaces for potential targeted delivery. Therefore, in these tough times, NDDS and nanotechnology
can be a safeguard to humanity.