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Coronaviruses

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ISSN (Print): 2666-7967
ISSN (Online): 2666-7975

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Letter Article

Utilizing Zebrafish Animal Model as a Helping Hand for COVID-19 Infection

Author(s): Yashbir Singh*, Heenaben Patel, Amit Chaudhary and S. Deepa

Volume 2, Issue 2, 2021

Published on: 15 September, 2020

Page: [272 - 274] Pages: 3

DOI: 10.2174/2666796701999200915144017

Abstract

Background: The Zebrafish animal model has the potential use to study COVID19 infection in-depth due to its genetic similarity with humans. It has antiviral property. As we know, SARS-CoV-2 is an RNA virus, which has a high genetic mutation rate, therefore difficult to understand its structure. It is a great way to understand the genetic dynamics of Zebrafish, which is related to orthologous human genes.

Objective: The study aims to validate the possible role of the Zebrafish animal model in the COVID19 diagnosis.

Methods: We have reviewed a lot of literature towards the Zebrafish model and tried to explore the possible connection in the diagnosis of COVID19.

Result: We observed a very close bridge between the Zebrafish model and COVID19 towards possible drug discovery diagnosis.

Conclusion: This research will be helpful to unlock the mechanism clues, finding new therapeutic targets, and understanding adaptability to host.

Keywords: Pandemic, COVID19, zebrafish, drug discovery, machine learning, therapeutic target.

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