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Current Nutrition & Food Science

Editor-in-Chief

ISSN (Print): 1573-4013
ISSN (Online): 2212-3881

Review Article

Fatty Acids Recommendations: Controversies and Updates

Author(s): Nadine N. Abdelhadi* and Mousa N. Ahmad

Volume 17, Issue 3, 2021

Published on: 07 August, 2020

Page: [288 - 292] Pages: 5

DOI: 10.2174/1573401316666200807203806

Price: $65

Abstract

Background: The reduction in the intake of dietary fat has traditionally been the cornerstone of dietary recommendations of many of the leading health organizations as a key measure to prevent cardiometabolic diseases. However, dietary fat recommendations are sometimes contrasting. In addition, many consumers and food manufacturers are still confused about the effects of fatty acids on coronary heart disease after decades of focus on the low-fat diet.

Objectives: To provide an overview of the recently available evidence on the effect of fatty acids on cardiometabolic risk and the various dietary recommendations related to reducing fat in the diet. It will also highlight the effect of the isocaloric substitution of fat by other macronutrients.

Methodology: The Cochrane Central Register of Controlled Trials, PubMed, Medline, Clinical trials.gov, Google Scholar, Science Direct, ADI, and WHO database were searched through to March 2020.

Results: Recent evidence demonstrates that higher dietary intakes of saturated fatty acids are associated with an increased risk of coronary heart disease which is consistent with the previous scientific evidence. In addition, recent findings indicate that replacing total saturated fatty acids with polyunsaturated fatty acids, monosaturated fatty acids and high-quality carbohydrates reduces cardiometabolic risk.

Conclusion: Higher dietary intakes of saturated fatty acids are associated with an increased coronary heart disease risk. Recent scientific evidence highlights the importance of replacing total saturated fat with more healthy alternatives including polyunsaturated fatty acids, monosaturated fatty acids, and high-quality carbohydrates which is consistent with the latest recommendations of the updated guidelines.

Keywords: Fatty acids, cardiometabolic risk, dietary recommendations, saturated fatty acids, polyunsaturated fatty acids, monosaturated fatty acids.

Graphical Abstract
[1]
Liu AG, Ford NA, Hu FB, Zelman KM, Mozaffarian D, Kris-Etherton PM. A healthy approach to dietary fats: understanding the science and taking action to reduce consumer confusion. Nutr J 2017; 16(1): 53.
[http://dx.doi.org/10.1186/s12937-017-0271-4] [PMID: 28854932]
[2]
Li Y, Hruby A, Bernstein AM, et al. Saturated fats compared with unsaturated fats and sources of carbohydrates in relation to risk of Coronary heart disease: a prospective cohort study. J Am Coll Cardiol 2015; 66(14): 1538-48.
[http://dx.doi.org/10.1016/j.jacc.2015.07.055] [PMID: 26429077]
[3]
Dehghan M, Mente A, Zhang X, et al. Prospective Urban Rural Epidemiology (PURE) study investigators. Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study. Lancet 2017; 390(10107): 2050-62.
[http://dx.doi.org/10.1016/S0140-6736(17)32252-3] [PMID: 28864332]
[4]
Zong G, Li Y, Wanders AJ, et al. Intake of individual saturated fatty acids and risk of coronary heart disease in US men and women: two prospective longitudinal cohort studies. BMJ 2016; 355: i5796.
[http://dx.doi.org/10.1136/bmj.i5796] [PMID: 27881409]
[5]
Praagman J, Beulens JWJ, Alssema M, et al. The association between dietary saturated fatty acids and ischemic heart disease depends on the type and source of fatty acid in the European Prospective Investigation into Cancer and Nutrition-Netherlands cohort. Am J Clin Nutr 2016; 103(2): 356-65.
[http://dx.doi.org/10.3945/ajcn.115.122671] [PMID: 26791181]
[6]
Guasch-Ferré M, Babio N, Martínez-González MA, et al. PREDIMED Study Investigators. Dietary fat intake and risk of cardiovascular disease and all-cause mortality in a population at high risk of cardiovascular disease. Am J Clin Nutr 2015; 102(6): 1563-73.
[http://dx.doi.org/10.3945/ajcn.115.116046] [PMID: 26561617]
[7]
Wang DD, Li Y, Chiuve SE, et al. Association of specific dietary fats with total and cause-specific mortality. JAMA Intern Med 2016; 176(8): 1134-45.
[http://dx.doi.org/10.1001/jamainternmed.2016.2417] [PMID: 27379574]
[8]
Jousilahti P, Laatikainen T, Peltonen M, et al. Primary prevention and risk factor reduction in coronary heart disease mortality among working aged men and women in eastern Finland over 40 years: population based observational study. BMJ 2016; 352: i721.
[http://dx.doi.org/10.1136/bmj.i721] [PMID: 26932978]
[9]
Sacks FM, Lichtenstein AH, Wu JHY, et al. American Heart Association. Dietary fats and cardiovascular disease: a presidential advisory from the American Heart Association. Circulation 2017; 136(3): e1-e23.
[http://dx.doi.org/10.1161/CIR.0000000000000510] [PMID: 28620111]
[10]
WHO and FAO joint consultation: fats and oils in human nutrition. Nutr Rev 1995; 53(7): 202-5.
[PMID: 7494623]
[11]
Burlingame B. fats and fatty acids in human nutrition joint. FAO/WHO Expert Consultation, Geneva 2008.
[12]
Piepoli MF, Hoes AW, Agewall S, et al. ESC Scientific Document Group. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J 2016; 37(29): 2315-81.
[http://dx.doi.org/10.1093/eurheartj/ehw106] [PMID: 27222591]
[13]
U.S. Department of Health and Human Services and U.S. Department of Agriculture. 2015-2020 Dietary Guidelines for Americans 8th Edition 2015; Available at: http://health.gov/dietaryguidelines/2015/guidelines/
[14]
Heart and Stroke Foundation of Canada. Heart and Stroke position statements 2019; Available at: https://www.heartandstroke.ca/heart-and-stroke-position-statements

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