Tecoma stans (L.) Juss. ex Kunth has shown potent antidiabetic effect in the past; however,
none of the studies have been carried out to explore its effect in diabetic complications including
diabetic retinopathy and nephropathy. Thus, this review will aim to explore and propose multiple
hypotheses regarding its mechanism of action in diabetic complications which includes reduction in
oxidative stress, inflammation, angiogenesis, lipid profile correction and direct anti-glycemic effects.
A detailed review including most of the articles, which includes research as well as reviews, available
on the internet regarding the concerned topic was performed. The review includes MEDLINE
databases using keywords along with their combinations, such as diabetic complications, plants in
diabetes, Tecoma stans, renin oxidative stress, inflammation, angiogenesis, diabetic retinopathy, α-
glucosidase and α-amylase, among several others. Mostly English-language articles were selected.
Since it has already been reported in various studies that Tecoma stans exhibit anti-diabetic effect,
however no information regarding its effects in diabetic complications were reported. This review
presents the data which aids in confirming that Tecoma stans can provide promising results in oxidative
stress, inflammation, angiogenesis and lipid peroxidation. Furthermore, it has been depicted that
Tecoma stans has the potential for α-glucosidase inhibition. The mechanism below can explain that
Tecoma stans can be used in diabetic complications of diabetic nephropathy and retinopathy.
Tecoma stans may provide an effective natural product to treat hyperglycaemia and prevent subsequent
diabetic complications which includes nephropathy and retinopathy.