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Endocrine, Metabolic & Immune Disorders - Drug Targets

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ISSN (Print): 1871-5303
ISSN (Online): 2212-3873

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Research Article

Effect of Diets with Different Lipid’s Sources On Serum and Brain Fatty Acids Profile: Experimental Model

Author(s): Nora H. Slobodianik, Paula D. Perris, María Cecilia Mambrin, Inés Fernandez and María Susana Feliu*

Volume 20, Issue 4, 2020

Page: [625 - 631] Pages: 7

DOI: 10.2174/1871530319666191120114032

Price: $65

Abstract

Background: The importance of diet in health is widely accepted and recognized. Diet lipid profile is important to prevent chronic diseases and improve the quality of an individual’s life.

Objective: The objective of this report is to analyze the effect of different sources of dietary lipids with standard and high concentration on growing rats.

Methods: Experimental diets contained 15 or 42% kcal of fat, provided by butter (B), olive oil (O), high oleic sunflower oil (HO), and sunflower oil (S). Control diet (C) was normocaloric with 15% kcal of fat provided by soy oil. All diets were complete in the other nutrients according to AIN 1993 and were administered for 40 days.

Results: Daily intake was similar in all groups. The administration of these diets provoked changes in serum fatty acid profile in response to the different sources of dietary lipids used; no changes were observed in the brain´s fatty acids.

Conclusion: These results would suggest that the organism tries first to supply the brain´s fatty acid needs at the expense of its modification in serum.

Keywords: Nutrition, fatty acids, lipids, diets, rats, brain.

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