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Current Alzheimer Research

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ISSN (Print): 1567-2050
ISSN (Online): 1875-5828

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Review Article

Assessment of Memory Impairment in Early Diagnosis of Alzheimer’s Disease

Author(s): Martin Vyhnálek*, Hana Marková, Jan Laczó, Rossana De Beni and Santo Di Nuovo

Volume 16, Issue 11, 2019

Page: [975 - 985] Pages: 11

DOI: 10.2174/1567205016666191113125303

Price: $65

Abstract

Memory impairment has been considered as one of the earliest clinical hallmarks of Alzheimer’s disease. This paper summarizes recent progress in the assessment of memory impairment in predementia stages. New promising approaches of memory assessment include evaluation of longitudinal cognitive changes, assessment of long-term memory loss, evaluation of subjective cognitive concerns and testing of other memory modalities, such as spatial memory. In addition, we describe new challenging memory tests based on memory binding paradigms that have been recently developed and are currently being validated.

Keywords: Elderly, memory impairment, Alzheimer's disease, mild cognitive impairment, subjective cognitive decline, neuropsychological assessment, memory binding, spatial memory.

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