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Current Drug Metabolism

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ISSN (Print): 1389-2002
ISSN (Online): 1875-5453

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Mini-Review Article

Current Designs and Developments of Fucoidan-based Formulations for Cancer Therapy

Author(s): Phuong H.L. Tran and Thao T.D. Tran*

Volume 20, Issue 12, 2019

Page: [933 - 941] Pages: 9

DOI: 10.2174/1389200220666191007154723

Price: $65

Abstract

Background: Natural nanostructure materials have been involved in antitumor drug delivery systems due to their biocompatibility, biodegradation, and bioactive properties.

Methods: These materials have contributed to advanced drug delivery systems in the roles of both bioactive compounds and delivery nanocarriers. Fucoidan, a valuable ocean material used in drug delivery systems, has been exploited in research on cancer and a variety of other diseases.

Results: Although the uniqueness, structure, properties, and health benefits of fucoidan have been mentioned in various prominent reviews, current developments and designs of fucoidan-based formulations still need to be assessed to further develop an effective anticancer therapy. In this review, current important formulations using fucoidan as a functional material and as an anticancer agent will be discussed. This article will also provide a brief principle of the methods that incorporate functional nanostructure materials in formulations exploiting fucoidan.

Conclusion: Current research and future perspectives on the use of fucoidan in anticancer therapy will advance innovative and important products for clinical uses.

Keywords: Fucoidan, drug delivery system, nanotechnology, functional nanomaterials, anticancer, nanocarriers.

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