Abstract
Here we report a greener approach for the synthesis of enamines from enols of 1,3-alkyl-2- thioxodihydropyrimidine-4,6(1H,5H)-dione (thiobarbituric acid) acid using ammonium chloride and ethanol as solvents. This protocol removes the need for catalysts or harsh conditions.
Keywords: Thiobarbituric acid, enols, enamines, greener approach, ammonium chloride, HPLC.
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