Abstract
Many biologically active compounds possess 1-sulfonyl pyrrolidine structural motif. Therefore, the development of facile methods for the preparation of these compounds in optically pure form is relevant. One of the regio- and stereoselective approaches to the pyrrolidine derivatives is cycloaddition. Thus, this review article is an attempt to survey literature describing synthetic methods for the preparation of 1-sulfonyl pyrrolidine derivatives via various cycloaddition reactions.
Keywords: Pyrrolidines, sulfonylamides, cycloadditions, heterocycles, stereoselectivity, synthesis.
Graphical Abstract
Call for Papers in Thematic Issues
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