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Current Protein & Peptide Science

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ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

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Review Article

Research Progress of Bioactive Proteins from the Edible and Medicinal Mushrooms

Author(s): Rong Zhou, Zhao Kun Liu*, Ye Ni Zhang, Jack Ho Wong, Tzi Bun Ng* and Fang Liu*

Volume 20, Issue 3, 2019

Page: [196 - 219] Pages: 24

DOI: 10.2174/1389203719666180613090710

Price: $65

Abstract

For centuries, mushrooms have been widely used as traditional Chinese medicine in Asia. Apart from polysaccharides and some small-molecule components, such as flavones, polyphenols and terpenes, mushrooms produce a large number of pharmaceutically active proteins, which have become popular sources of natural antitumor, antimicrobial, immunoenhancing agents. These bioactive proteins include lectins, laccases, Ribosome Inactivating Proteins (RIPs), nucleases, and Fungal Immunomodulatory Proteins (FIPs). The review is to summarize the characterstics of structure and bioactivities involved in antitumor, antiviral, antifungal, antibacterial and immunoenhancing activities of proteins from edible mushrooms, to better understand their mechanisms, and to direct research.

Keywords: Antimicrobial, antitumor, immunoenhancement, mushroom, protein, Asia.

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