Login Register Cart 0
Generic placeholder image

Current Pharmaceutical Analysis

Editor-in-Chief

ISSN (Print): 1573-4129
ISSN (Online): 1875-676X

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

Visible Light Detection of Dopamine Enhanced by Cloud Point Extraction

Author(s): Asiye Aslıhan Avan and Hayati Filik*

Volume 15, Issue 5, 2019

Page: [528 - 534] Pages: 7

DOI: 10.2174/1573412914666180427152544

Price: $65

Abstract

Background: Monitoring of DA, in the presence of other chemical analogues such as epinephrine, norepinephrine, serotonin, ascorbic acid, uric acid, catechol, phenethylamine, tyramine, and tyrosine, is crucial in the diagnosis and mechanistic understanding of human neuropathology. Therefore, the determination of DA at trace levels has become a very important analytical task, as part of health safety and forensic analysis.

Introduction: A cloud point extraction (CPE) process was developed for the isolation and detection of dopamine in food, urine, and pharmaceutical samples.

Methods: In this procedure, dopamine was derivatized with o-phthalaldehyde (OPA) and sodium sulphite in aqueous solution. The isoindole derivative was synthesized by the reaction of OPA and sodium sulphite with the amino group of dopamine and the resulted isoindole derivatives were extracted by cloud point extraction. After extraction process, the concentration of enriched analyte was measured by UV-VIS spectrophotometry. The parameters affecting the CPE such as concentration of surfactant and electrolyte, equilibration temperature and time and pH of sample solution were investigated.

Results: After optimization of the CPE conditions, the linear range of 8-80 µM (without extraction 100- 1000 µM) was established for dopamine with detection limit at 2.6 µM.

Conclusion: The developed extraction procedure was applied to the quantification of dopamine in chocolate, urine, and pharmaceutical samples. The study ensures a promising strategy for the detection of dopamine in the presence of biological constituents, e.g. ascorbic acid, uric acid, and serotonin.

Keywords: Dopamine, cloud point extraction, spectrophotometry, food, urine, pharmaceutical, analysis.

« Previous Next »
Graphical Abstract

[1]
Engelborghs, S.; Marescau, B.; De Deyn, P.P. Amino acids and biogenic amines in cerebrospinal fluid of patients with parkinson’s disease. Neurochem. Res., 2003, 28(8), 1145-1150.
[2]
Mora, F.; Segovia, G.; Del Arco, A.; De Blas, M.; Garrido, P. Stress, neurotransmitters, corticosterone and body-brain integration. Brain Res., 2012, 1476, 71-85.
[3]
Liu, J.; Yuan, L.; Dong, X. Recent advances in analytical techniques for the determination of dopamine. Int. J. Chem. Stud., 2015, 3(3), 39-45.
[4]
Perry, M.; Li, Q.; Kennedy, R.T. Review of recent advances in analytical techniques for the determination of neurotransmitters. Anal. Chim. Acta, 2009, 653(1), 1-22.
[5]
Guo, L.; Zhang, Y.; Li, Q. Spectrophotometric determination of dopamine hydrochloride in pharmaceutical, banana, urine and serum samples by potassium ferricyanide-Fe(III). Anal. Sci., 2009, 25(12), 1451-1455.
[6]
Nour El-Dien, F.A.; Zayed, M.A.; Mohamed, G.G.; El-Nahas, R.G. Two spectrophotometric assays for dopamine derivatives in pharmaceutical products and in biological samples of schizophrenic patients using copper tetramine complex and triiodide reagent. J. Biomed. Biotechnol., 2005, 2005(1), 1-9.
[7]
Rami, R.N.; Sreedevi, G.; Prabhavathi, K.; Chakravarthy, I.E. Spectrophotometric determination of dopamine in pharmaceutical formulations. J. Anal. Chem., 2005, 60(3), 284-285.
[8]
Berzas, N.J.J.; Lemus, G.J.M.; Buitrago, L.P. Spectrophotometric determination of dopamine and methyldopa with metaperiodate by flow injection analysis. Fresenius J. Anal. Chem., 1995, 353(2), 221-223.
[9]
Madrakian, T.; Afkhami, A.; Khalafi, L.; Mohammadnejad, M. Spectrophotometric determination of catecholamines based on their oxidation reaction followed by coupling with 4-aminobenzoic acid. J. Braz. Chem. Soc., 2006, 17(7), 1259-1265.
[10]
Nagaraja, P.; Murthy, K.C.S.; Rangappa, K.S.; Gowda, N.M.M. Spectrophotometric methods for the determination of certain catecholamine derivatives in pharmaceutical preparations. Talanta, 1998, 46(1), 39-44.
[11]
Shishehbore, M.R.; Asgharpoor, A.; Nasirizadeh, N. A novel kinetic spectrophotometric method for the determination of dopamine in biological and pharmaceutical samples. J. Chem.,, 2013. Article ID 819460, 6 pages, doi:10.1155/2013/819460.
[12]
Mamiński, M.; Olejniczak, M.; Chudy, M.; Dybko, A.; Brzózka, Z. Spectrophotometric determination of dopamine in microliter scale using microfluidic system based on polymeric technology. Anal. Chim. Acta, 2005, 540(1), 153-157.
[13]
Zhang, X.; Chen, X.; Kai, S.; Wang, H.Y.; Yang, J.; Wu, F.G.; Chen, Z. Highly sensitive and selective detection of dopamine using one-pot synthesized highly photoluminescent silicon nanoparticles. Anal. Chem., 2015, 87(6), 3360-3365.
[14]
Oppolzer, D.; Moreno, I.; da Fonseca, B.; Passarinha, L.; Barroso, M.; Costa, S.; Queiroz, J.A.; Gallardo, E. Analytical approach to determine biogenic amines in urine using microextraction in packed syringe and liquid chromatography coupled to electrochemical detection. Biomed. Chromatogr., 2013, 27, 608-614.
[15]
El-Beqqali, A.; Kussak, A.; Abdel-Rehim, M. Determination of dopamine and serotonin in human urine samples utilizing microextraction online with liquid chromatography/ electrospray tandem mass spectrometry. J. Sep. Sci., 2007, 30(3), 421-424.
[16]
He, J.; Liu, Z.; Ren, L.; Liu, Y.; Dou, P.; Qian, K.; Chen, H.Y. On-line coupling of in-tube boronate affinity solid phase microextraction with high performance liquid chromatography-electrospray ionization tandem mass spectrometry for the determination of cis-diol biomolecules. Talanta, 2010, 82(1), 270-276.
[17]
Auger, J.; Boulay, R.; Jaillais, B.; Delion-Vancassel, S. Analysis of biogenic amines by solid-phase microextraction and high-performance liquid chromatography with electrochemical detection. J. Chromatogr. A, 2000, 870(1-2), 395-403.
[18]
Naccarato, A.; Gionfriddo, E.; Sindona, G.; Tagarelli, A. Development of a simple and rapid solid phase microextraction-gaschromatography-triple quadrupole mass spectrometry method for the analysis of dopamine, serotonin and norepinephrine in human urine. Anal. Chim. Acta, 2014, 810, 17-24.
[19]
Zhang, X.; Xu, S.; Lim, J.M.; Lee, Y.I. Molecularly imprinted solid phase microextraction fiber for trace analysis of catecholamines in urine and serum samples by capillary electrophoresis. Talanta, 2012, 99, 270-276.
[20]
Abdolmohammad-Zadeh, H.; Talleb, Z. Dispersive solid phase micro-extraction of dopamine from human serum using a nano-structured Ni-Al layered double hydroxide, and its direct determination by spectrofluorometry. Mikrochim. Acta, 2012, 179(1-2), 25-32.
[21]
Khezeli, T.; Daneshfar, A. Dispersive micro-solid-phase extraction of dopamine, epinephrine and norepinephrine from biological samples based on green deep eutectic solvents and Fe3O4@MIL-100 (Fe) core-shell nanoparticles grafted with pyrocatechol. RSC Advances, 2015, 5(80), 65264-65273.
[22]
Wu, H.F.; Lin, C.H. Direct combination of immersed single-drop microextraction with atmospheric pressure matrix-assisted laser desorption/ionization tandem mass spectrometry for rapid analysis of a hydrophilic drug via hydrogen-bonding interaction and comparison with liquid-liquid extraction and liquid-phase microextraction using a dual gauge microsyringe with a hollow fiber. Rapid Commun. Mass Spectrom., 2006, 20(16), 2511-2515.
[23]
Cakal, C.; Ferrance, J.P.; Landers, J.P.; Caglar, P. Microchip extraction of catecholamines using a boronic acid functional affinity monolith. Anal. Chim. Acta, 2011, 690(1), 94-100.
[24]
Paleologos, E.K.; Giokas, D.L.; Karayannis, M.I. Micelle-mediated separation and cloud-point extraction. TrAC-Trend. Anal. Chem., 2005, 24(5), 426-436.
[25]
Liang, R.; Wang, Z.; Xu, J.H.; Li, W.; Qi, H. Novel polyethylene glycol induced cloud point system for extraction and back-extraction of organic compounds. Separ. Purif. Tech., 2009, 66(2), 248-256.
[26]
Purkait, M.K.; Banerjee, S.; Mewara, S.; DasGupta, S.; De, S. Cloud point extraction of toxic eosin dyes using Triton-100 as nonionic surfactant. Water Res., 2005, 39(16), 3885-3890.
[27]
Zuman, P. Reactions of orthophthalaldehyde with nucleophiles. Chem. Rev., 2004, 104(7), 3219-3238.
[28]
Mana, H.; Spohn, U. Rapid and selective determination of ammonium by fluorimetric flow injection analysis. Fresenius J. Anal. Chem., 2000, 366(8), 825-829.
[29]
Filik, H.; Çetintaş, G. Determination of sulfite in water and dried fruit samples by dispersive liquid-liquid microextraction combined with UV-Vis fiber optic linear array spectrophotometry. Food Anal. Methods, 2012, 5(6), 1362-1367.
[30]
Takadate, A.; Fujino, H.; Obasa, M.; Goya, S. Fluorogenic reaction of sulfite with o-phthalaldehyde. Chem. Pharm. Bull., 1986, 34(3), 1172-1175.
[31]
Carrez, M.C. Estimation of lactose in milk. Ann. Chim. Anal., 1908, 14, 187-189.

Rights & Permissions Print Cite
Article Metrics
50
2
© 2024 Bentham Science Publishers | Privacy Policy