Abstract
A growing body of evidence has indicated that endophytic microorganism is one of the important prolific producers of natural products with potential application in new drug discovery. On the basis of the extensive literature search, new endophyte-related findings in secondary metabolites uncovered during the past 11 years (2006-2016) were summarized in this review according to their bioactive properties.
Keywords: Endophyte, symbiotic microbe, secondary metabolite, natural product, natural drug, drug lead.
Graphical Abstract
Call for Papers in Thematic Issues
Ayurvedic medicinal therapeutic approaches for inflammatory and neurodegenerative disorders
Usually, in our elderly population, neurodegenerative disorders occur due to neuron death. Alzheimer?s disease (AD) is an irreversible and progressive neurodegenerative disease. Dementia is the leading cause of AD, which affects about 30 million people worldwide. According to the World Alzheimer report 2018, a new case of dementia develops every ...read more
Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
Biotransformation is the reaction catalyzed by biological catalysts of either isolated enzymes or whole cell cultures of microorganisms. This process has been extensively applied in the conversion of bioactive terpenoids with high regio- and stereospecifity. This process has been also applied in the lead discovery and development. Aspergillus niger has ...read more
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