Abstract
Identification of transformation products and elucidation of degradation pathways of pharmaceuticals in the environment is a challenging task due to the numerous compounds, their low concentrations, and complexity of the environmental matrices. This manuscript summarizes present knowledge about main degradation routes of pharmaceuticals in the environment and review published methods and approaches for their determination in environmental samples, with a special emphasis on the mass spectrometry and nuclear magnetic resonance techniques.
Keywords: Pharmaceuticals, environment, fate, degradation path, liquid chromatography, mass spectrometry, nuclear magnetic resonance.
Current Organic Chemistry
Title:Transformation Products of Pharmaceuticals in the Environment: Formation and Analysis
Volume: 22 Issue: 10
Author(s): Sandra Babic*, Martina Biosic and Irena Skoric
Affiliation:
- Department of Analytical Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulicev trg 19, Zagreb,Croatia
Keywords: Pharmaceuticals, environment, fate, degradation path, liquid chromatography, mass spectrometry, nuclear magnetic resonance.
Abstract: Identification of transformation products and elucidation of degradation pathways of pharmaceuticals in the environment is a challenging task due to the numerous compounds, their low concentrations, and complexity of the environmental matrices. This manuscript summarizes present knowledge about main degradation routes of pharmaceuticals in the environment and review published methods and approaches for their determination in environmental samples, with a special emphasis on the mass spectrometry and nuclear magnetic resonance techniques.
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Cite this article as:
Babic Sandra *, Biosic Martina and Skoric Irena , Transformation Products of Pharmaceuticals in the Environment: Formation and Analysis, Current Organic Chemistry 2018; 22 (10) . https://dx.doi.org/10.2174/1385272822666171122160926
DOI https://dx.doi.org/10.2174/1385272822666171122160926 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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