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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Review Article

The Synthetic and Biological Attributes of Pyrazole Derivatives: A Review

Author(s): Jaya Dwivedi*, Swapnil Sharma, Sonika Jain and Aarti Singh

Volume 18, Issue 11, 2018

Page: [918 - 947] Pages: 30

DOI: 10.2174/1389557517666170927160919

Price: $65

Abstract

Pyrazole nucleus is a unique structural scaffold which acts as an interesting template for combinatorial as well as medicinal chemistry. This review presents a detailed overview on the synthesis, QSAR and pharmacological applications of pyrazole. In addition, it covers most recent reports on structural modifications on pyrazole illustrating vital structural activity relationship.

Keywords: Combinatorial chemistry, medicinal chemistry, pharmacological activity, pharmacophore, pyrazole, QSAR.

Graphical Abstract

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