Abstract
Background: Chitosan thermoresponsive hydrogel is non-covalent crosslinked intelligent hydrogel. The compositions of the hydrogel determine its gelling property associated with particular structure-interaction effects. Simple and mild preparations as well as desirable bioactivities allow chitosan thermoresponsive hydrogels extensively applied in drug delivery and tissue engineering, especially the exciting proceeding in enzyme-free cell harvest and vascular embolic agent.
Objective: This paper reviewed the classification of chitosan thermoresponsive hydrogels based on different components, emphasizing their gelling capacities, mechanism and applications in biomedical areas.
Keywords: Chitosan, thermoresponsive hydrogel, sol-gel reversible, drug delivery, tissue engineering, cell culture, wound dressing, embolic agent.
Current Organic Chemistry
Title:The Novel Medical Thermoresponsive Hydrogel Derived from Chitosan
Volume: 22 Issue: 7
Author(s): Ming Kong and Xiguang Chen*
Affiliation:
- College of Marine Life Science, Ocean University of China, 5 Yushan Road, Qingdao, 26603,China
Keywords: Chitosan, thermoresponsive hydrogel, sol-gel reversible, drug delivery, tissue engineering, cell culture, wound dressing, embolic agent.
Abstract: Background: Chitosan thermoresponsive hydrogel is non-covalent crosslinked intelligent hydrogel. The compositions of the hydrogel determine its gelling property associated with particular structure-interaction effects. Simple and mild preparations as well as desirable bioactivities allow chitosan thermoresponsive hydrogels extensively applied in drug delivery and tissue engineering, especially the exciting proceeding in enzyme-free cell harvest and vascular embolic agent.
Objective: This paper reviewed the classification of chitosan thermoresponsive hydrogels based on different components, emphasizing their gelling capacities, mechanism and applications in biomedical areas.
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Cite this article as:
Kong Ming and Chen Xiguang *, The Novel Medical Thermoresponsive Hydrogel Derived from Chitosan, Current Organic Chemistry 2018; 22 (7) . https://dx.doi.org/10.2174/1385272821666170811111651
DOI https://dx.doi.org/10.2174/1385272821666170811111651 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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