A Comprehensive Review on Phytochemistry and Pharmacological Effects of Stinging Nettle (Urtica dioica)

Author(s): Mona Semalty, Lokesh Adhikari, Divya Semwal, Anita Chauhan, Akash Mishra, Rupali Kotiyal, Ajay Semalty*

Journal Name: Current Traditional Medicine

Volume 3 , Issue 3 , 2017

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Graphical Abstract:


Background and Objective: Urtica dioica (stinging nettle), a member of the Urticaceae family, has been used in various traditional systems of medicines since ancient times especially for joint pain, arthritis and prostate problems. Its roots and leaves contain a wide variety of bioactive constituents like sterols, fatty acids, lectins terpenes, phenylpropanes, lignans and coumarins. The leaves and root extract shows various activities like hypoglycemic, anti-inflammatory, antiproliferative, antioxidant, hypolipemic, antirheumatic, anticarcinogenic and antiviral activity. It shows its effects through the inhibition of aromatase, 5 α-reductase, cell proliferation and Na+, K+-ATPase inhibition.

Conclusion: The article reviews the phytochemistry and phytopharmacology of the plant.

Keywords: Alopecia, analgesic, anti-arthritic, antihypertensive, anti-inflammatory, 5 alpha reductase inhibitor, BPH, herbal remedy, nettle, urtica.

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Article Details

Year: 2017
Published on: 21 November, 2017
Page: [156 - 167]
Pages: 12
DOI: 10.2174/2215083803666170502120028
Price: $25

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