Structural, Functional and Evolutionary Aspects of Seed Globulins

Title:Structural, Functional and Evolutionary Aspects of Seed Globulins

Volume: 24 Issue: 3

Author(s): Pooja Kesari, Neetu, Anchal Sharma, Madhusudhanarao Katiki, Pramod Kumar, Bhola R. Gurjar, Shailly Tomar, Ashwani K. Sharma and Pravindra Kumar

Affiliation:

Keywords: Globulins, cupin superfamily, 7S vicilin, 11S legumin, evolution, seed storage protein.

Abstract: Globulins are a major class of seed storage proteins which were thought to be enzymatically inactive. These proteins belong to the most ancient cupin superfamily. They can be graded into 11S legumin type and 7S vicilin type based on their sedimentation coefficients. Members from both classes share structural homology are thought to have evolved from either one-domain germin predecessor by duplication or by horizontal gene transfer of two-domain gene from bacteria to eukaryotes. Globulins are known to define the nutritional quality of the seeds, however, they are also involved in sucrose binding, desiccation, defense against microbes, hormone binding and oxidative stress etc. Major drawback with globulins is their tendency to bind to IgE. Studying structural-functional behavior of such protein can help in modifying proteins for enhanced functionality in food processing industries.

Cite this article as:

Kesari Pooja, Neetu , Sharma Anchal, Katiki Madhusudhanarao, Kumar Pramod, Gurjar R. Bhola, Tomar Shailly, Sharma K. Ashwani and Kumar Pravindra, Structural, Functional and Evolutionary Aspects of Seed Globulins, Protein & Peptide Letters 2017; 24 (3) . https://dx.doi.org/10.2174/0929866523666161220112641