Login Register Cart 0
Generic placeholder image

Current Drug Safety

Editor-in-Chief

ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Case Studies

Severe Coagulation Disorder and Thrombocytopenia Associated with Tigecycline – Case Report and Review of Literature

Author(s): Sami Giryes, Zaher S. Azzam, Reem Ismael-Badarneh, Norberto Krivoy and Gidon Berger

Volume 12, Issue 1, 2017

Page: [7 - 9] Pages: 3

DOI: 10.2174/1574886311666160920090714

Price: $65

Abstract

Herein, we report a 70-year-old male patient, with recurrent multiple hepatic abscesses, that was admitted to the internal medicine department for treatment of Carbapenem Resistant Escherichia Coli (CRE) bacteremia.

The patient was treated with Tigecycline; few days later, he developed "Disseminated Intravascular Coagulation (DIC)" like coagulation study abnormality that seemed to be related to Tigecycline treatment. Upon discontinuing it, the DIC-like condition was resolved.

Tigecycline should be considered as a possible etiological factor in patients with DIC-like, and this therapy should be withdrawn immediately in suspected cases.

Keywords: Coagulation disorder, DIC, hypofibrinogenemia, Tigecycline, thrombocytopenia.

« Previous

Rights & Permissions Print Cite
Article Metrics
125
4
4
© 2024 Bentham Science Publishers | Privacy Policy