Abstract
Exosomes and microvesicles, which are released by most of the cells, play important roles in intracellular correspondence by transferring DNA, messenger RNA, micro RNA, and other types of RNA and proteins. Exosomes and microvesicles may contribute to the distribution of cancers and diseases through delivering the pathogenic agents to the non-infected cells; in cancers, they can modify the cells in the tumor niche and lead them to transformation. In addition, these vesicles can affect stem cell activity and their physiological properties. On the other hand, exosomes and microvesicles can be applied in the therapeutic strategies as they are small, non-viral, flexible and able to cross biological barriers. In this review, we focused on some details about the exosomes and microvesicles both functionally and structurally.
Keywords: Cell communication, epigenetics, metastasis, microvesicles, reprograming.
Current Stem Cell Research & Therapy
Title:A Comprehensive Review on Exosomes and Microvesicles as Epigenetic Factors
Volume: 12 Issue: 1
Author(s): Behnaz Bakhshandeh, Mohammad Amin Kamaleddin and Khadijeh Aalishah
Affiliation:
Keywords: Cell communication, epigenetics, metastasis, microvesicles, reprograming.
Abstract: Exosomes and microvesicles, which are released by most of the cells, play important roles in intracellular correspondence by transferring DNA, messenger RNA, micro RNA, and other types of RNA and proteins. Exosomes and microvesicles may contribute to the distribution of cancers and diseases through delivering the pathogenic agents to the non-infected cells; in cancers, they can modify the cells in the tumor niche and lead them to transformation. In addition, these vesicles can affect stem cell activity and their physiological properties. On the other hand, exosomes and microvesicles can be applied in the therapeutic strategies as they are small, non-viral, flexible and able to cross biological barriers. In this review, we focused on some details about the exosomes and microvesicles both functionally and structurally.
Export Options
About this article
Cite this article as:
Bakhshandeh Behnaz, Kamaleddin Amin Mohammad and Aalishah Khadijeh, A Comprehensive Review on Exosomes and Microvesicles as Epigenetic Factors, Current Stem Cell Research & Therapy 2017; 12 (1) . https://dx.doi.org/10.2174/1574888X11666160709211528
DOI https://dx.doi.org/10.2174/1574888X11666160709211528 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Modulation of Human Keratinocyte Responses to Solar UV by Plant Polyphenols As a Basis for Chemoprevention of Non-Melanoma Skin Cancers
Current Medicinal Chemistry Camptothecins and Lung Cancer: Improved Delivery Systems by Aerosol
Current Cancer Drug Targets Membrane Transporters in Physiological Barriers of Pharmacological Importance
Current Pharmaceutical Design Molecular Aspects of FKBP51 that Enable Melanoma Dissemination
Current Molecular Pharmacology Potential Interactions of Carotenoids with Other Bioactive Food Components in the Prevention of Chronic Diseases
Current Bioactive Compounds Progress in Gene Delivery by Cationic Lipids : Guanidinium-Cholesterol-Based Systems as an Example
Current Drug Targets Trizbenzim, Cu-Trizbenzim and Zn-Trizbenzim as G-Quadruplex Inducing and Stabilizing Compounds on Human Telomeric Sequence and their Anticancer Properties
Anti-Cancer Agents in Medicinal Chemistry Antitumor Potential and Possible Targets of Phenothiazine-Related Compounds
Current Drug Targets Targeting Histone Deacetylase Inhibitors for Anti-Malarial Therapy
Current Topics in Medicinal Chemistry Micro Arrays and Biochips: Applications and Potential in Genomics and Proteomics
Current Genomics Circumscribing the Conformational Peptide Epitope Landscape
Current Pharmaceutical Design Editorial: [Cytokines as Anti-Cancer Agents Rational, Results and Perspectives (Guest Editor: S. Mocellin)]
Current Medicinal Chemistry Impact of PET on the Radiation Treatment of Hodgkins Lymphoma
Current Radiopharmaceuticals AIDS Related Viruses, their Association with Leukemia, and Raf Signaling
Current HIV Research Biosafety Challenges for Use of Lentiviral Vectors in Gene Therapy
Current Gene Therapy Non-Photoinduced Biological Properties of Verteporfin
Current Medicinal Chemistry Bronchial Asthma and Lung Cancer
Current Respiratory Medicine Reviews Recent Advances in Hematopoietic Stem Cell-Mediated Regeneration
Recent Patents on Regenerative Medicine Inventions Designed to Enhance Drug Delivery Across Epithelial and Endothelial Cells Through the Paracellular Pathway
Recent Patents on Drug Delivery & Formulation Drug Resistance and Apoptosis in Cancer Treatment: Development of New Apoptosis-Inducing Agents Active in Drug Resistant Malignancies
Current Medicinal Chemistry - Anti-Cancer Agents