Abstract
Background: Cancer is one of the most serious illnesses of our civilization. Therefore, scientists of different disciplines try to find new treatment strategies and new chemical molecules which might be useful in a cancer treatment.
Objective: The goal of this work is to perform the most significant achievements in the area of chemotherapeutic treatment, published during the last two years.
Methods: We reviewed almost 80 contributions, searching for new molecules with anticancer activity and treatment strategies.
Results: We have presented tens of new anticancer molecules interacting with DNA or affecting cell cycle and new findings in this area. These compounds are chemically synthesized as well as are isolated from natural sources. The discovered molecules may induce cancer cells apoptosis, improve other cancer treatments, such as radiotherapy or reduce side effects of chemotherapy.
Conclusion: The review shows that the cancer battle is still in progress and the combined studies in different disciplines, devoted to this subject, are a rapidly expanding area.
Keywords: Anticancer molecules, cancer treatment, drugs, drug delivery, drug development, tumor, mechanisms of action.
Medicinal Chemistry
Title:New Hopes in Cancer Battle - A Review of New Molecules and Treatment Strategies
Volume: 12 Issue: 8
Author(s): Marika Turek, Magdalena Krzyczmonik and Piotr Balczewski
Affiliation:
Keywords: Anticancer molecules, cancer treatment, drugs, drug delivery, drug development, tumor, mechanisms of action.
Abstract: Background: Cancer is one of the most serious illnesses of our civilization. Therefore, scientists of different disciplines try to find new treatment strategies and new chemical molecules which might be useful in a cancer treatment.
Objective: The goal of this work is to perform the most significant achievements in the area of chemotherapeutic treatment, published during the last two years.
Methods: We reviewed almost 80 contributions, searching for new molecules with anticancer activity and treatment strategies.
Results: We have presented tens of new anticancer molecules interacting with DNA or affecting cell cycle and new findings in this area. These compounds are chemically synthesized as well as are isolated from natural sources. The discovered molecules may induce cancer cells apoptosis, improve other cancer treatments, such as radiotherapy or reduce side effects of chemotherapy.
Conclusion: The review shows that the cancer battle is still in progress and the combined studies in different disciplines, devoted to this subject, are a rapidly expanding area.
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Cite this article as:
Turek Marika, Krzyczmonik Magdalena and Balczewski Piotr, New Hopes in Cancer Battle - A Review of New Molecules and Treatment Strategies, Medicinal Chemistry 2016; 12 (8) . https://dx.doi.org/10.2174/1573406412666160502153700
DOI https://dx.doi.org/10.2174/1573406412666160502153700 |
Print ISSN 1573-4064 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6638 |
Call for Papers in Thematic Issues
Carbohydrates in Computational and Medicinal Chemistry
Carbohydrates are the most essential organic molecules and are involved in the maintenance of various physiological and metabolic processes in living organisms. Carbohydrate-based compounds have come to the attention of researchers because of their significant contributions to biological functions, such as cell development and cell proliferation, connections between several cells, ...read more
Recent Advances in the Medicinal Chemistry of Cancer
Scope of the Thematic Issue: Correlation between structure and function is one of the important aspects of the success of anti-cancer compounds associated with their structure-activity interactions, physiology, biochemical, molecular, and genetic processes. Overcoming these obstacles is key to obtaining further insights into developments in rational drug design, bioorganic chemistry, ...read more
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