ISSN (Print): 2468-4228
ISSN (Online): 2468-4236
ISSN (Print): 2468-4228
ISSN (Online): 2468-4236
Aims & Scope
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Editor(s): Massimo Buscema and Enzo Grossi
eISBN: 978-1-60805-042-0, 2009
This Ebook covers the emerging and most important theories underlying artificial intelligence applications in a variety of medical problems. It is written for physicians, researchers, engineers, statisticians and advanced students who wish to increase their familiarity with different topics of modern mathematics related to predictive medicine. Both theoretical and applied aspects are presented in this book. Many illustrative mathematical explanations and worked-out examples are given. This book features contributions by nine noted experts from leading medical centers worldwide, which should prove to be of considerable interest to the readers.
Editor(s): Octavian C. Ioachimescu
Guest-Editor(s): Teofilo Lee-Chiong
eISBN: 978-1-60805-153-3, 2011
Contemporary Sleep Medicine should be of interest to a large number of readers interested in sleep medicine. It is divided into two parts – one for patients or simple readers and another for physicians or advanced readers. The Ebook explores new research grounds for sleep disorders. These include novel methodologies for epidemiological research and strategies for curing individuals who suffer from sleep disorders. The volumes seek to update interested readers on the latest advances in the uncharted territory of sleep medicine.
Author(s): Marcia Radanovic and Leticia Lessa Mansur
eISBN: 978-1-60805-108-3, 2011
Language is the most versatile and fascinating of all human cognitive functions, constituting a field of interest in very different areas, from Linguistics to Speech Therapy, from Philosophy to Computational Sciences, including Psychology, Neurology, Biology, and Social Sciences. The scope of this E-book is to provide the reader with an update on topics relevant to neurolinguistics such as new cognitive models of comprehension and production of normal language, new perspectives on the understanding of aphasic symptoms and the interface between language and other cognitive functions – functional neuroimaging and language. This E-book will be of interest both for teachers and researchers in Neurosciences and Linguistics as well as for professionals who treat patients with disorders of language and communication, such as Neurologists, Psychiatrists, Psychologists, Neuropsychologists, Speech Therapists, and Occupational Therapists, among many others.
Editor(s): Susan A. Adubato and Deborah E. Cohen
eISBN: 978-1-60805-031-4, 2011
This ebook addresses the impact of prenatal exposure to alcohol, and Fetal Alcohol Spectrum Disorders (FASD). It presents a compilation of current research by leading experts in the field and serves as a guide to future directions in FASD research, interventions and treatment. The book includes a comprehensive compendium of our knowledge of the dangers of prenatal alcohol exposure and covers ways to screen and intervene with pregnant women, diagnosis and treatment to ameliorate the effects of prenatal alcohol exposure (through the lifespan), and other related issues, such as building a state infrastructure of health services and legislation. The ebook is intended as a textbook for graduate courses relevant to FASD.
Editor(s): Giuseppe Rizzo
Co-Editor(s): Domenico Arduini
eISBN: 978-1-60805-044-4, 2010
Congenital heart defects (CHD) are the most frequent malformation in the human fetus and are the leading cause of mortality due to malformations in the first year of life. Despite its clinical importance screening performed by ultrasonographic examination during the second trimester of pregnancy has shown disappointingly low detection rates mainly due to the difficulties in obtaining an adequate examination of the fetal heart. Four-dimensional (4D) ultrasound of the fetal heart has been recently suggested as a tool to improve the detection rate of CHD by decreasing the dependency on operator skills required in two-dimensional ultrasound scans but up to now no practical manuals are available in describing its application in clinical practice for the study of fetal heart. The objective of this Ebook is to explain the role of 4D during second trimester examination and in fetuses with CHD. T
Editor(s): Misa Nakamura and Kennichi Kakudo
eISBN: 978-1-60805-073-4, 2010
The WHO report estimates that 12 million people will be diagnosed with some form of cancer this year. In addition, the report predicts that more than 7 million people will die early from the disease. Together, the number of cancer cases and deaths from cancer are expected to increase by one percent each year. Cancer research has seen remarkable advancements, including the multi-step carcinogenesis theory and the identification of a cancer stem cell. These advancements are being applied to clinical therapies targeting the oncogene. In addition, the function of the gene product is becoming clear through analysis of the intracellular signaling of the oncogene. As a result, it has become clear that the morphologies of the cancers depend on the kind of the abnormal gene. Of course, these differences would influence patient’s life and death and is summarized by specialists in this area. This theme includes the full range of human diseases regarding medical genetics, biochemistry, microbiology, immunology, anatomy, pathology, structural biology, molecular cell biology, neuroscience and developmental biology. The eBook contains articles written by specialists in this area. It should prove to be of great use to clinicians and scientists in all medical fields.
Editor(s): Pankaj K. Bhowmik, Saikat K. Basu and Aakash Goyal
eISBN: 978-1-60805-090-1, 2009
The first volume of this Ebook series brings together the most recent advances from leading experts in the burgeoning field of biotechnology. This comprehensive text adopts a multidisciplinary approach and covers agricultural biotechnology, industrial and environmental biotechnology, pharmaceutical sciences and drug developments from plant sources, biochemical and molecular studies on gene expression, forestry, genetic engineering, gene delivery approaches, plant tissue culture and biochemical techniques/methods/protocols involved in different areas of plant biotechnology. This Ebook should prove to be a valuable resource for plant biotechnologists, plant biologists, biochemists, molecular biologists, pharmacologists, and pharmacists; agronomists, plant breeders, and geneticists; ethnobotanists, ecologists, and conservationists; medical practitioners and nutritionists; research investigators in industry, federal laboratories, and universities; and students and teachers in the biological and biomedical sciences at undergraduate and postgraduate levels.
Editor(s): Elisabetta Tosti and Raffaele Boni
eISBN: 978-1-60805-182-3, 2011
Events of reproduction occurring from meiotic resumption of the immature oocyte up to its exit from the second meiotic block following activation will be revealed. Morphological modifications of the oocyte during maturation will be related to signal transduction mechanisms involving primary or secondary messengers. A detailed view will be addressed to genetic and epigenetic control of oocyte maturation. At fertilization, reciprocal gamete activation and novel knowledge related to sperm factor and cascade mechanisms occurring in the oocyte will be focused. A detailed description of ion currents occurring during fertilization will depict another point of view of oocyte activation mechanisms, further supporting for their complexity.
Finally, all basic information related to this short time lapse will be considered in relation to clinical application of assisted reproductive technologies. New frontiers, such as stem cells and cloning technologies, will be analyzed and future applications and improvements will be hypothesised.
Editor(s): Ana Lúcia Leitão
eISBN: 978-1-60805-223-3, 2011
Fungi are extremely versatile microorganisms as a biotechnology tool having the advantage of being relatively easy to grow, thus making them suitable for large scale production. Fungi have been successfully employed for biotransformations ranging from food manufacturing to drug design. Mycofactories comprise a substantial share of significant current research in the area of fungal biotechnology, and constitutes an effort to compile high level research in this domain. Topics include applications of fungi as a main source for the production of enzymes, manufacture of food derivatives, pigments and additives, and applications in bioremediation.
Editor(s): Yinghui Dan
Co-Editor(s): David W. Ow
eISBN: 978-1-60805-248-6, 2011
ISBN: 978-1-60805-532-6 ISSN: 2211-2936 (Print)
Plant transformation technology has played a critical role in advancing biotechnology and fundamental research and evolved as a science. This book describes the breakthrough technologies in all aspects of plant transformation in the last 27 years, which have been contributed by the world leading experts in the field. This e-book is one of the first books that covers critical technologies in all aspects of plant transformation to plant biologists and molecular biologists from industrial, academic and governmental organizations. It should greatly benefit postdoctoral associates and graduate and undergraduate students in the plant biology community.
Author(s): Olivier Renaudet and Nicolas Spinelli
eISBN: 978-1-60805-277-6, 2011
The interactions between carbohydrates and proteins have been extensively explored in a wide range of physiological and pathological processes over several decades. The recent emergence of glycomics has strengthened this interest and notably contributed to spectacular progress in understanding how carbohydrates mediate and regulate complex biological events. Synthesis and Biological Applications of Glycoconjugates gives a summary of contemporary findings in glycoconjugate research. Readers will be updated on major achievements in chemical methods and biological applications employed in modern glycomics. The Ebook should be of interest to a broad community of students and professional researchers in both academia and industry.
Editor(s): Michel Goldberg
eISBN: 978-1-60805-171-7, 2010
ISBN: 978-1-60805-606-4 ISSN: 2589-3076 (Print) ISSN: 2210-2841 (Online)
This volume is the 1st in a series of Ebooks that bridges the gap between advances in science and clinical practice in odontology. Recent advances in biology, materials science and tissue engineering are increasingly viewed as being of enormous clinical potential. Stem cell research has opened up the possibility of reconstructing teeth from the association of epithelial and mesanchymal embryonic or adult cells, as an exciting alternative to metal implants. This Ebook will examine the multifunctional nature of a group of proteins known as the amelogenins. Latest studies indicate that this protein regulates the initiation and growth of hydroxyapatite crystals during the mineralization of enamel. In addition, amelogenins organize enamel rods during tooth development, and also aid in the development of cementum by directing cells that form the cementum to the root surface of the teeth. The aim of this book is to serve as a bridge between basic biology and biomaterial sciences, and to inform clinicians about the implications of recent advances within these fields for clinical practice.