ISSN (Print): 2468-4228
ISSN (Online): 2468-4236
ISSN (Print): 2468-4228
ISSN (Online): 2468-4236
Aims & Scope
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Editor(s): Ichiro Shimizu
eISBN: 978-1-60805-293-6, 2012
Liver cancer, cirrhosis and nonalcoholic fatty liver disease are observed predominately in men. Being male or female is believed to be an important human variable that affects health and liver disease throughout the life span. However, few works have been published on the biological mechanisms underlying gender specific differences in liver disease. Several mechanisms underlying sex-associated differences of progression of liver disease are demonstrated in this e-book based on biological factors as estrogen and hepatic iron stores. Readers will gain a better understanding of the pathogenesis of these sex-associated differences in liver disease and on how to design healthcare for liver disease more effectively for individuals belonging to both genders. The e-book should be a useful reference on gender specific medicine for counselors and clinicians as well as for patients with chronic liver disease.
Author(s): Bashir M. Matata and Maqsood M. Elahi
eISBN: 978-1-60805-286-8, 2011
This e-book discusses the molecular relationship between biological systems and risk factors for in-utero oxidative insults, maternal health and the impact on fetus at different critical developmental time windows (prenatal or even postnatal). Plausibly, prenatal and early postnatal periods are the most critical “windows” to oxidative stress programming insults. Pro-oxidative stress is a common feature of many conditions associated with adverse fetal growth and/or preterm birth, such as pre-eclampsia, diabetes, smoking, malnutrition or excessive nutrition, infection or inflammation. Oxidative stress insults may be directly linked to or associated with many genetic, nutritional and environmental risk factors that contribute to risks of adverse fetal growth or preterm birth. This e-book should be a valuable reference for medical researchers and working professionals interested in congenital defects.
Editor(s): Adaucto Bellarmino Pereira-Netto
eISBN: 978-1-60805-298-1, 2012
Brassinosteroids: Practical Applications in Agriculture and Human Health provides a comprehensive overview on the practical applications of brassinosteroids (BRs) in plant biology (including stress tolerance, growth and development) and human health (anticancer, antiviral and anti-inflammatory activity). The book assures readers a high-quality review of practical applications with a selection of contributions from an international panel of expert researchers. The book suggests new opportunities for professionals to effectively increase the supply of quality food and other plant-derived products, and to improve human health. This book is a reference guide for the performance and interpretation of applications of brassinosteroids to agronomists, chemists, physicians and plant physiologists.
Editor(s): Klaus Podar and Kenneth C. Anderson
eISBN: 978-1-60805-297-4, 2012
Multiple Myeloma (MM), the second most common blood cancer in adults, is a clonal plasma cell malignancy within the bone marrow characterized by osteolytic bone lesions, renal disease, and immunodeficiency. It is now well established that MM cell- induced disruption of the bone marrow homeostasis between the highly organized cellular and extracellular compartments supports MM cell proliferation, survival, migration, and drug resistance via activation of various signaling pathways. Based on this knowledge, the prototypic drugs thalidomide, bortezomib, and lenalidomide, which target both MM cells and the bone marrow microenvironment, have already fundamentally changed treatment options of this disease. Indeed, their benefit is now not only shown in relapsed and refractory disease but they also improve overall response, duration of response, and progression-free and overall survival when used as part of first-line regimens. However, despite new insights into MM pathogenesis and exciting derived therapeutic advances, MM still remains incurable. Ongoing studies are therefore aiming to further delineate mechanisms of MM pathogenesis within the bone marrow to identify novel agents with enhanced cytotoxicity and decreased drug resistance to improve patient outcome.
Multiple Myeloma - A New Era of Treatment Strategies is devoted to contributions from eminent scientists providing readers with comprehensive accounts of the most recent developments in the field of MM research. It addresses the interests of scientists and clinical investigators in MM research as well as other fields of oncology, in which the microenvironment is believed to play an important role.
Author(s): Anastasios K. Markopoulos
eISBN: 978-1-60805-113-7, 2009
This textbook provides a comprehensive overview of the part of dentistry that links basic physiologic and pathophysiologic mechanisms to frequently encountered problems in dental practice. Themes that are covered include the structure and function of the cells of oral mucosa, the biology of bone, the functions of oral mucosa, some important aspects on oral microbial flora and biofilms and finally the current principles on mastication, swallowing and speech. The knowledge of basic sciences is essential in oral biology, helping to understand the nature and behavior of cells, tissues and organs in health and disease. It is an easy-to-read, relatively brief but a comprehensive Ebook appropriate for undergraduate and graduate dental students as well as for practicing clinicians.
Editor(s): S.C Tjong
eISBN: 978-1-60805-040-6, 2009
This authoritative reference provides update information on the fundamental aspects and applications of biomaterials and biomedical sciences. It includes nickel-titanium alloys with superelasticity and shape memory effect, bioactive bone cement for orthopedic applications, and new research trends in polymer nanocomposites. This Ebook also describes the response of cells to ionizing radiation such as DNA damage responses in zebrafish. With chapters contributed by eminent scientists in the field of biophysics, biomaterials and biomedical engineering, this is a useful reference for graduate students, researchers and professionals in biomedical sciences and technologies.
Editor(s): Francisco Sánchez-Bayo, Paul J. van den Brink and Reinier M. Mann
eISBN: 978-1-60805-121-2, 2011
Ecological Impacts of Toxic Chemicals presents a comprehensive, yet readable account of the known disturbances caused by all kinds of toxic chemicals on both aquatic and terrestrial ecosystems. Topics cover the sources of toxicants, their fate and distribution through the planet, their impacts on specific ecosystems, and their remediation by natural systems. Each chapter is written by well-known specialists in those areas, for the general public, students, and even scientists from outside this field. The book intends to raise awareness of the dangers of chemical pollution in a world dominated by industry and globalization of resources. Because the problems are widespread and far reaching, it is hoped that confronting the facts may prompt better management practices at industrial, agricultural and all levels of management, from local to governmental, so as to reduce the negative impacts of chemical contaminants on our planet.
Editor(s): Matt T. Bianchi, Verne S. Caviness and Sydney S. Cash
eISBN: 978-1-60805-017-8, 2012
This book covers novel approaches using networks and oscillations and it will serve as a catalyst for translating these exciting advancements into the clinical arena. This collection of articles aims to accelerate the widespread clinical translation of network approaches by providing practical information accessible to clinicians in neurology and psychiatry - fields that are uniquely poised to implement these developments in clinical treatment of brain diseases. It should be a useful resource for researchers and working professionals in neurological and psychiatric academic centers.
Editor(s): Liliana Olmos, Carlos Alberto Torres and Rich Van Heertum
eISBN: 978-1-60805-268-4, 2011
ISBN: 978-1-60805-336-0 ISSN: 2211-727X (Print)
Globalization has emerged as one of the key social, political and economic forces of the twenty-first century, challenging national borders, long established institutions of governance and cultural norms and behaviors around the world. Yet how has it affected education? The series explores the complex and multivariate ways in which changing global paradigms have influenced education, democracy and citizenship from Latin America, Europe and Africa to Asia, the Middle East and North America. It seeks to unearth how these changes have manifest themselves in daily classroom experiences for teachers and administrators the world over and how recent events might influence future change.
Editor(s): Anthony N. Rezitis
eISBN: 978-1-60805-263-9, 2012
ISBN: 978-1-60805-699-6 ISSN: 2589-1472 (Print) ISSN: 1879-7415 (Online)
The aim of this e-book series is to publish high quality economic research in agricultural and applied economics. It particularly fosters quantitative studies which make original contribution on important economic issues, the results of which help to understand and solve real economic problems. This volume contains research papers focusing on the areas of agricultural policy, agricultural price volatility, agricultural finance and cooperatives, consumption economics, firm production and organization, human capital convergence, international economics and multinational business, investment decisions in organic agriculture, market structure and industry studies. The research papers of this volume make use of recent methodological approaches and provide conclusions which are useful to both private sector participants and policy-makers.
eISBN: 978-1-60805-098-7, 2010
ISBN: 978-1-60805-397-1 ISSN: 2589-1472 (Print) ISSN: 1879-7415 (Online)
The aim of the eBook series of Research Topics in Agricultural & Applied Economics (RTAAE) is to publish high quality economic researches applied to both the agricultural and non-agricultural sectors of the economy. The subject areas of this eBook series include, among others, supply and demand analysis, technical change and productivity, industrial organization, labor economics, growth and development, environmental economics, marketing, business economics and finance. By covering a broad variety of economic research topics, this eBook series should prove to be of considerable interest to a wide spectrum of academic, agricultural and applied economic researchers and scientists, as well as to industry specialists and government policy makers.
eISBN: 978-1-60805-243-1, 2011
ISBN: 978-1-60805-698-9 ISSN: 2589-1472 (Print) ISSN: 1879-7415 (Online)
The aim of the Ebook series of Research Topics in Agricultural & Applied Economics (RTAAE) is to publish high quality economic researches applied to both the agricultural and non-agricultural sectors of the economy. The subject areas of this Ebook series include, among others, supply and demand analysis, technical change and productivity, industrial organization, labor economics, growth and development, environmental economics, marketing, business economics and finance. By covering a broad variety of economic research topics, this Ebook series should prove to be of considerable interest to a wide spectrum of academic, agricultural and applied economic researchers and scientists, as well as to industry specialists and government policy makers.