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Reviews on Recent Clinical Trials

Editor-in-Chief

ISSN (Print): 1574-8871
ISSN (Online): 1876-1038

Immunotherapy for Non-Small Cell Lung Cancer - Finally a Hint of Hope

Author(s): Gonzalo Recondo, Gonzalo Recondo, Fernando Galanternik, Martín Greco, Máximo de la Vega, E. Diaz Cantón and Matías E. Valsecchi

Volume 11, Issue 2, 2016

Page: [87 - 92] Pages: 6

DOI: 10.2174/1574887111666160330121349

Price: $65

Abstract

Lung cancer is a major public health problem worldwide and the leading cause of cancerrelated mortality in developed countries. Significant advances have been made especially with the discovery of targeted agents. However, only a small proportion of patients carry activating mutations; until recently conventional chemotherapy and angiogenesis inhibitors were the preferred treatment for the vast majority of patients. Now, the successful experience of anti-PD-1 agents may have opened the door to a novel and previously unexplored dimension in the treatment of lung cancer: immunotherapy. In this mini-review we will discuss the current applications and future consequences related this topic, paying special attention to the clinical studies that constitute the scientific evidence to supports its use.

Keywords: Immunotherapy, lung cancer, nivolumab, PD-1, squamous cell carcinoma.

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