Abstract
Currently, many novel therapies are available for physicians treating cancer; some of them are associated with adverse cardiac events. One of the most worrisome cardiac event is QT prolongation, which is a risk factor for developing the potentially fatal torsade de pointe. Many classes of drugs, both anticancer and concomitant agents, are involved in this issue. We report a review of old and new commonly used agents with torsadogenic potential.
Keywords: Adverse cardiac events, cancer, QT prolongation, through QT study, torsade de point.
Reviews on Recent Clinical Trials
Title:QT Prolongation and Anticancer Drugs: Is it a Cardiologist’s Worry? The Oncologist’s Point of View
Volume: 11 Issue: 3
Author(s): Francesca Aroldi, Tiziana Prochilo, Elena Bonini and Alberto Zaniboni
Affiliation:
Keywords: Adverse cardiac events, cancer, QT prolongation, through QT study, torsade de point.
Abstract: Currently, many novel therapies are available for physicians treating cancer; some of them are associated with adverse cardiac events. One of the most worrisome cardiac event is QT prolongation, which is a risk factor for developing the potentially fatal torsade de pointe. Many classes of drugs, both anticancer and concomitant agents, are involved in this issue. We report a review of old and new commonly used agents with torsadogenic potential.
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Cite this article as:
Aroldi Francesca, Prochilo Tiziana, Bonini Elena and Zaniboni Alberto, QT Prolongation and Anticancer Drugs: Is it a Cardiologist’s Worry? The Oncologist’s Point of View, Reviews on Recent Clinical Trials 2016; 11 (3) . https://dx.doi.org/10.2174/1574887111666160226150650
DOI https://dx.doi.org/10.2174/1574887111666160226150650 |
Print ISSN 1574-8871 |
Publisher Name Bentham Science Publisher |
Online ISSN 1876-1038 |
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