Abstract
Marine environment exhibits an enormous diversity of organisms which contains an abundant source of polysaccharides. As polymer matrix carriers, marine-based polymers possess several valuable properties including high stability, non-toxicity, hydrophilicity, biodegradability, with low production cost. Despite notable biological activities of these natural polymers, there are certain limitations in exploring their functions in applications of nano-sized drug delivery systems. The review aims to demonstrate exceptional characteristics of marine-based polymers including fucoidan, alginate, carrageenan, hyaluronic acid, chondroitin sulfate, and chitosan as well as provide perspectives of current publications on their nanoparticle formulations for biomedical applications.
Keywords: Marine-based polymers, nanoparticles, biodegradable, drug delivery, natural polymer.
Current Pharmaceutical Design
Title:Perspectives of Engineered Marine Derived Polymers for Biomedical Nanoparticles
Volume: 22 Issue: 19
Author(s): Khanh Thi My Tran, Toi Van Vo, Wei Duan, Phuong Ha-Lien Tran and Thao Truong-Dinh Tran
Affiliation:
Keywords: Marine-based polymers, nanoparticles, biodegradable, drug delivery, natural polymer.
Abstract: Marine environment exhibits an enormous diversity of organisms which contains an abundant source of polysaccharides. As polymer matrix carriers, marine-based polymers possess several valuable properties including high stability, non-toxicity, hydrophilicity, biodegradability, with low production cost. Despite notable biological activities of these natural polymers, there are certain limitations in exploring their functions in applications of nano-sized drug delivery systems. The review aims to demonstrate exceptional characteristics of marine-based polymers including fucoidan, alginate, carrageenan, hyaluronic acid, chondroitin sulfate, and chitosan as well as provide perspectives of current publications on their nanoparticle formulations for biomedical applications.
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Cite this article as:
Tran Thi My Khanh, Vo Van Toi, Duan Wei, Tran Ha-Lien Phuong and Tran Truong-Dinh Thao, Perspectives of Engineered Marine Derived Polymers for Biomedical Nanoparticles, Current Pharmaceutical Design 2016; 22 (19) . https://dx.doi.org/10.2174/1381612822666160217124735
DOI https://dx.doi.org/10.2174/1381612822666160217124735 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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