Recent Advancement and Technological Aspects of Pulsatile Drug Delivery System - A Laconic Review

Title:Recent Advancement and Technological Aspects of Pulsatile Drug Delivery System - A Laconic Review

Volume: 18 Issue: 10

Author(s): Vinay Pandit, Ajay Kumar, Mahendra S. Ashawat, Chander P. Verma and Pravin Kumar*

Affiliation:

• Department of Pharmaceutics, Laureate Institute of Pharmacy, Kathog, Kangra (H.P) - 177101,India

Keywords: Pulsatile, herbal, chronotherapy, lag time, drug delivery, drug formation.

Abstract: Background: Pulsatile drug delivery system (PDDS) shows potential significance in the field of drug delivery to release the maximum amount of drug at a definite site and at specific time. PDDS are mainly time controlled delivery devices having a definite pause period for drug release, which is not affected by acidity, alkalinity, motility and enzymes present in the gastrointestinal tract. Pulsatile medication possess the potential to deliver the drugs in the therapy of diseases where drug dose is essential during sleep, drugs having greater first pass metabolism and absorption at precise location in digestive tract.

Cite this article as:

Pandit Vinay, Kumar Ajay, Ashawat S. Mahendra, Verma P. Chander and Kumar Pravin*, Recent Advancement and Technological Aspects of Pulsatile Drug Delivery System - A Laconic Review, Current Drug Targets 2017; 18 (10) . https://dx.doi.org/10.2174/1389450117666160208144343