Abstract
Coral-derived microorganisms have been a major focus of many research efforts on marine ecology in recent decades. Importantly, research on bioactive compounds from these diverse microorganisms, which include fungi and bacteria, has experienced an explosive growth during the past five years. This has unveiled the ecological roles of these microorganisms, which prevent antifouling, inhibit pathogenic bacteria, and deter predators in ocean ecosystems. Moreover, the structural diversity and pharmacological activity of the compounds produced by these microorganisms have also been studied extensively, leading not only to an understanding their roles within ecosystems, but also the potential value of their use in human health. In this review, 258 marine natural products, including polyketides, terpenoids, meroterpenoids, alkaloids, peptides, shikimates and lipids, all discovered in the past 24 years, are presented. 146 references are cited.
Keywords: Alkaloids, antifouling, antimicroorganisms, antitumor, biodiversity, coral-derived microorganisms, polyketides.
Current Medicinal Chemistry
Title:Biological and Chemical Diversity of Coral-Derived Microorganisms
Volume: 22 Issue: 32
Author(s): Xue-Mei Hou, Ru-Fang Xu, Yu-Cheng Gu, Chang-Yun Wang and Chang-Lun Shao
Affiliation:
Keywords: Alkaloids, antifouling, antimicroorganisms, antitumor, biodiversity, coral-derived microorganisms, polyketides.
Abstract: Coral-derived microorganisms have been a major focus of many research efforts on marine ecology in recent decades. Importantly, research on bioactive compounds from these diverse microorganisms, which include fungi and bacteria, has experienced an explosive growth during the past five years. This has unveiled the ecological roles of these microorganisms, which prevent antifouling, inhibit pathogenic bacteria, and deter predators in ocean ecosystems. Moreover, the structural diversity and pharmacological activity of the compounds produced by these microorganisms have also been studied extensively, leading not only to an understanding their roles within ecosystems, but also the potential value of their use in human health. In this review, 258 marine natural products, including polyketides, terpenoids, meroterpenoids, alkaloids, peptides, shikimates and lipids, all discovered in the past 24 years, are presented. 146 references are cited.
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Cite this article as:
Hou Xue-Mei, Xu Ru-Fang, Gu Yu-Cheng, Wang Chang-Yun and Shao Chang-Lun, Biological and Chemical Diversity of Coral-Derived Microorganisms, Current Medicinal Chemistry 2015; 22 (32) . https://dx.doi.org/10.2174/0929867322666151006093755
DOI https://dx.doi.org/10.2174/0929867322666151006093755 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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