Abstract
Regenerative medicine is a multidisciplinary field where continued progress relies on the incorporation of a diverse set of technologies from a wide range of disciplines within medicine, science and engineering. This review describes how one such technique, mathematical modelling, can be utilised to improve the tissue engineering of organs and stem cell therapy. Several case studies, taken from research carried out by our group, ACTREM, demonstrate the utility of mechanistic mathematical models to help aid the design and optimisation of protocols in regenerative medicine.
Keywords: Regenerative medicine, tissue engineering, stem cell therapy, stem cells, mathematical modelling, computational modelling.
Current Stem Cell Research & Therapy
Title:The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy
Volume: 11 Issue: 8
Author(s): Greg Lemon, Sebastian Sjoqvist, Mei Ling Lim, Neus Feliu, Alexandra B. Firsova, Risul Amin, Ylva Gustafsson, Annika Stuewer, Elena Gubareva, Johannes Haag, Philipp Jungebluth and Paolo Macchiarini
Affiliation:
Keywords: Regenerative medicine, tissue engineering, stem cell therapy, stem cells, mathematical modelling, computational modelling.
Abstract: Regenerative medicine is a multidisciplinary field where continued progress relies on the incorporation of a diverse set of technologies from a wide range of disciplines within medicine, science and engineering. This review describes how one such technique, mathematical modelling, can be utilised to improve the tissue engineering of organs and stem cell therapy. Several case studies, taken from research carried out by our group, ACTREM, demonstrate the utility of mechanistic mathematical models to help aid the design and optimisation of protocols in regenerative medicine.
Export Options
About this article
Cite this article as:
Lemon Greg, Sjoqvist Sebastian, Lim Ling Mei, Feliu Neus, Firsova B. Alexandra, Amin Risul, Gustafsson Ylva, Stuewer Annika, Gubareva Elena, Haag Johannes, Jungebluth Philipp and Macchiarini Paolo, The Use of Mathematical Modelling for Improving the Tissue Engineering of Organs and Stem Cell Therapy, Current Stem Cell Research & Therapy 2016; 11 (8) . https://dx.doi.org/10.2174/1574888X10666151001115942
DOI https://dx.doi.org/10.2174/1574888X10666151001115942 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Hydrogen Sulfide: A New Tool to Design and Develop Drugs
Clinical Anti-Inflammatory & Anti-Allergy Drugs (Discontinued) Extrahepatic Targets and Cellular Reactivity of Drug Metabolites
Current Medicinal Chemistry Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection
Current Drug Metabolism Natural Products as a Source of Antiarrhythmic Drugs
Mini-Reviews in Medicinal Chemistry Emerging Therapies for Type 2 Diabetes
Current Drug Therapy Melatonin in the Biliary Tract and Liver: Health Implications
Current Pharmaceutical Design C/EBP Transcription Factors in Lung Disease
Current Respiratory Medicine Reviews “Impact of Smoking Cessation Treatment” on Lung Function and Response Rate in EGFR Mutated Patients: A Short-Term Cohort Study
Recent Patents on Anti-Cancer Drug Discovery Mechanisms of Brain Signaling During Sepsis
Current Neuropharmacology Pulmonary Hypertension and Systemic Diseases
Current Drug Targets - Inflammation & Allergy Oligonucleotide Aptamers for Glioma Targeting: An Update
Central Nervous System Agents in Medicinal Chemistry Phytoestrogens and Prostate Cancer
Current Drug Targets Pharmacologic Modulators of Soluble Guanylate Cyclase/Cyclic Guanosine Monophosphate in the Vascular System - From Bench Top to Bedside
Current Vascular Pharmacology New Vectors and Strategies for Cardiovascular Gene Therapy
Current Gene Therapy The VHL Tumor Suppressor: Master Regulator of HIF
Current Pharmaceutical Design Relation Between Obstructive Sleep Apnea Syndrome and Resistant Hypertension - The Tip of the Iceberg
Current Respiratory Medicine Reviews In Situ Oxidative Stress and Atrial Cell Deaths in Patients with Valve Disease
Cardiovascular & Hematological Disorders-Drug Targets Telephone Follow-up of Older People After Hospital Admissions
Current Aging Science Oncolytic Coxsackievirus and the Mechanisms of its Effects on Cancer: A Narrative Review
Current Cancer Therapy Reviews Diabetes Beyond Insulin: Review of New Drugs for Treatment of Diabetes Mellitus
Current Drug Discovery Technologies