Abstract
This review presents most of the literature data about synthesis and biological activity of pyrazolo[4,3-c]heterocyclic derivatives. Pyrazolo[4,3-c]heterocyclic derivatives show the antimicrobial, anti-inflammatory, antiviral, antitumor, analgesic and antiphlogistic activities, and effects on the nervous and immune system. The broad spectrum of biological activity of pyrazolo[4,3-c]heterocyclic derivatives is the main reason for the preparation of new compounds containing this scaffold.
Keywords: Biological activity, pyrazolo[4, 3-c]heterocyclic derivatives; pyrazolo[4, 3-c]pyridines, pyrazolo[4, 3-c]quinolones; synthesis.
Mini-Reviews in Organic Chemistry
Title:Synthesis and Biological Activity of Pyrazolo[4,3-c]heterocyclic Derivatives: A Mini Review
Volume: 12 Issue: 4
Author(s): Anna Wojcicka and Lilianna Becan
Affiliation:
Keywords: Biological activity, pyrazolo[4, 3-c]heterocyclic derivatives; pyrazolo[4, 3-c]pyridines, pyrazolo[4, 3-c]quinolones; synthesis.
Abstract: This review presents most of the literature data about synthesis and biological activity of pyrazolo[4,3-c]heterocyclic derivatives. Pyrazolo[4,3-c]heterocyclic derivatives show the antimicrobial, anti-inflammatory, antiviral, antitumor, analgesic and antiphlogistic activities, and effects on the nervous and immune system. The broad spectrum of biological activity of pyrazolo[4,3-c]heterocyclic derivatives is the main reason for the preparation of new compounds containing this scaffold.
Export Options
About this article
Cite this article as:
Wojcicka Anna and Becan Lilianna, Synthesis and Biological Activity of Pyrazolo[4,3-c]heterocyclic Derivatives: A Mini Review, Mini-Reviews in Organic Chemistry 2015; 12 (4) . https://dx.doi.org/10.2174/1570193X12666150930224649
DOI https://dx.doi.org/10.2174/1570193X12666150930224649 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
Call for Papers in Thematic Issues
Navigating the 2D Universe in Organic Chemistry
This special issue explores the transformative impact of two-dimensional (2D) materials on the realm of organic chemistry, unraveling new possibilities for synthesis, functionalization, and applications of organic compounds. Focused on the unique chemistry within this novel dimension, the issue highlights breakthroughs in the field of 2D organic chemistry. Contributions are ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Fibroblast Growth Factor-Inducible 14: Multiple Roles in Tumor Metastasis
Current Molecular Medicine Hereditary Breast Cancer in Sub-Saharan Africa
Current Women`s Health Reviews Targeting Allosteric Control Mechanisms in Heat Shock Protein 70 (Hsp70)
Current Topics in Medicinal Chemistry Purine Analogues as Kinase Inhibitors: A Review
Recent Patents on Anti-Cancer Drug Discovery Cytotoxicity and Anti-inflammatory Activity of Flavonoid Derivatives Targeting NF-kappaB
Recent Patents on Inflammation & Allergy Drug Discovery Twist-BRD4 Complex: Potential Drug Target for Basal-like Breast Cancer
Current Pharmaceutical Design Antibodies and their Multivalent Constructs for Cancer Therapy
Protein & Peptide Letters Targeted Lipid Nanoparticles for Antisense Oligonucleotide Delivery
Current Pharmaceutical Biotechnology Comparison of Kernel and Decision Tree-based Algorithms for the Prediction of microRNAs Associated with Cancer
Current Bioinformatics Cinnamic Acid Derivatives as Anticancer Agents-A Review
Current Medicinal Chemistry PET in Anti-Cancer Drug Development and Therapy
Recent Patents on Anti-Cancer Drug Discovery FAT10: Function and Relationship with Cancer
Current Molecular Pharmacology Cardiovascular Biology of Interleukin-6
Current Pharmaceutical Design Pro-Inflammatory Mechanisms in Diabetic Neuropathy: Focus on the Nuclear Factor Kappa B Pathway
Current Drug Targets Obstacles and Opportunities for Cholinergic Drug Development in the Treatment of Cognitive Disorders
Current Pharmaceutical Design Anti-VEGF/VEGFR2 Monoclonal Antibodies and their Combinations with PD-1/PD-L1 Inhibitors in Clinic
Current Cancer Drug Targets Present Scenario of M-Cell Targeting Ligands for Oral Mucosal Immunization
Current Drug Targets Targeting the Epidermal Growth Factor Receptor Family in Radionuclide Therapy of Tumors – Signal Transduction and DNA Repair
Letters in Drug Design & Discovery DNA Methylation and Breast Cancer
Current Genomics A Practical Perspective on the Evaluation of Small Molecule CNS Penetration in Drug Discovery
Drug Metabolism Letters