Hypopituitarism in Neurocritical Patients: A Case Report

Author(s): Michele Iovino, Nicola Iovine, Fiorentino Mondillo, Edoardo Guastamacchia, Brunclla Licchelli, Vito A. Giagulli, Vincenzo Triggiani

Journal Name: Endocrine, Metabolic & Immune Disorders - Drug Targets
Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 16 , Issue 1 , 2016

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Background: Besides changes in pituitary hormones secretion observed during the acute phase of stroke as an adaptive response to injury or an effect of drugs, a true hypopituitarism due to ischemic and/or hemorrhagic damage at the hypothalamus and/or pituitary gland can develop after a stroke.

Case Report: We report a case of a 72-year-old woman showing clinical signs and laboratory data suggesting a secondary adrenal insufficiency following a recent acute brain ischemia. Cortisone therapy significantly improved this pituitary dysfunction.

Conclusions: Clinicians must pay attention to the hypothalamic-pituitary axis in neurocritical patients because hormonal replacement therapy may be life-saving.

Keywords: Adrenal insufficiency, hyponatremia, hypopituitarism, neuro-critical patients.

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Article Details

Year: 2016
Published on: 24 May, 2016
Page: [28 - 31]
Pages: 4
DOI: 10.2174/1871530315666150930121912
Price: $65

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