Abstract
Recent studies have shown that, in addition to its well-known erythropoietic effects, erythropoietin has anti-inflammatory, neuroprotective, and neurotrophic effects in different tissues including the retina and optic nerve. In this review, we made a comprehensive search to define the therapeutic potential of erythropoietin in retinal and optic nerve diseases that lead to blindness.
Keywords: Erythropoietin, erythropoietic effect, neuroprotective, optic neuritis, optic nerve, retina.
CNS & Neurological Disorders - Drug Targets
Title:Therapeutic Potential of Erythropoietin in Retinal and Optic Nerve Diseases
Volume: 14 Issue: 9
Author(s): Bekir Kucuk, Yakup Cevik, Ugur Acar and Gungor Sobaci
Affiliation:
Keywords: Erythropoietin, erythropoietic effect, neuroprotective, optic neuritis, optic nerve, retina.
Abstract: Recent studies have shown that, in addition to its well-known erythropoietic effects, erythropoietin has anti-inflammatory, neuroprotective, and neurotrophic effects in different tissues including the retina and optic nerve. In this review, we made a comprehensive search to define the therapeutic potential of erythropoietin in retinal and optic nerve diseases that lead to blindness.
Export Options
About this article
Cite this article as:
Kucuk Bekir, Cevik Yakup, Acar Ugur and Sobaci Gungor, Therapeutic Potential of Erythropoietin in Retinal and Optic Nerve Diseases, CNS & Neurological Disorders - Drug Targets 2015; 14 (9) . https://dx.doi.org/10.2174/1871527314666150821104800
DOI https://dx.doi.org/10.2174/1871527314666150821104800 |
Print ISSN 1871-5273 |
Publisher Name Bentham Science Publisher |
Online ISSN 1996-3181 |
Call for Papers in Thematic Issues
Diagnosis and treatment of central nervous system infectious diseases
Infectious diseases of the central nervous system (CNS) can be divided into bacterial, tuberculous, viral, fungal, parasitic infections, etc. Early etiological treatment is often the most crucial means to reduce the mortality rate of patients with central nervous system infections, reduce complications and sequelae, and improve prognosis. The initial clinical ...read more
Techniques of Drug Repurposing: Delivering a new life to Herbs & Drugs
Of late, with the adaptation of innovative approaches and integration of advancements made towards medical sciences as well as the availability of a wide range of tools; several therapeutic challenges are being translated into viable clinical solutions, with a high degree of efficacy, safety, and selectivity. With a better understanding ...read more
Trends and perspectives in the rational management of CNS disorders
Central nervous system (CNS) diseases enforce a significant global health burden, driving ongoing efforts to improve our understanding and effectiveness of therapy. This issue investigates current advances in the discipline, focusing on the understanding as well as therapeutic handling of various CNS diseases. The issue covers a variety of diseases, ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Topical Dermatological Drug Delivery: Quo Vadis?
Current Drug Delivery Antineovascular Agents in the Treatment of Eye Diseases
Current Pharmaceutical Design Erythropoietin in Stroke Therapy: Friend or Foe
Current Medicinal Chemistry Pathophysiology of the Vascular Wall and its Relevance for Cerebrovascular Disorders in Aged Rodents
Current Neurovascular Research Traumatic Spinal Cord Injury Alters Angiogenic Factors and TGF-Beta1 that may Affect Vascular Recovery
Current Neurovascular Research PDE5 Inhibitors in Non-Urological Conditions
Current Pharmaceutical Design Vasoactive Factors and Diabetic Retinopathy: Vascular Endothelial Growth Factor, Cycoloxygenase-2 and Nitric Oxide
Current Pharmaceutical Design Anti-Diabetic Effects of Isolated Lipids from Natural Sources through Modulation of Angiogenesis
Current Molecular Pharmacology Nucleoside Transporter Proteins
Current Vascular Pharmacology Neuronal and Glial Cell Abnormality as Predictors of Progression of Diabetic Retinopathy
Current Pharmaceutical Design Down-Regulation of Angiogenic Inhibitors: A Potential Pathogenic Mechanism for Diabetic Complications
Current Diabetes Reviews Prospective for Diagnosis and Treatment of Diabetic Retinopathy
Current Pharmaceutical Design The Impact of Oxidative Stress on Islet Transplantation and Monitoring the Graft Survival by Non-Invasive Imaging
Current Medicinal Chemistry Basic and Clinical Aspects of Gene Therapy for Retinopathy Induced by Diabetes
Current Gene Therapy Controversies in NSAIDs Use in Cataract Surgery
Current Pharmaceutical Design Unusual Clinical Manifestations of the Antiphospholipid Syndrome
Current Rheumatology Reviews Pharmacological Benefits of Active Components of Natural Products Against Traumatic Brain Injury - A Review
Current Pharmacogenomics and Personalized Medicine Vascular Changes of the Retina and Choroid in Systemic Lupus Erythematosus: Pathology and Pathogenesis
Current Neurovascular Research Polyphenols and Neuroprotection against Ischemia and Neurodegeneration
Mini-Reviews in Medicinal Chemistry ANN Classification and Modified Otsu Labeling on Retinal Blood Vessels
Current Signal Transduction Therapy