Abstract
The aim of this literature review is to investigate if volatile diterpenoids, a small group of compounds, found in some essential oils, have any of the various biological activities which are generally attributed to essential oils. The importance to emphasize is the fact, that in nature, the number of volatile and bio-active diterpenoids is very small. Different plant families have been investigated and their essential oils have been distilled, compounds were isolated and then analyzed. Almost all isolated diterpenoids showed to have cytotoxic, antioxidant or antimicrobial activities alone or more often in synergism with other essential oil compounds. For example labdane-type and abietane-type diterpenes have shown cytotoxicity against tumor cells and abietane-like compounds play an important role as antioxidants. For each isolated class of diterpenoids one or more biological activities can be observed.
Keywords: Biological properties, biosynthesis, essential oils, volatile diterpenoids.
Current Bioactive Compounds
Title:Biological Activity of Some Volatile Diterpenoids
Volume: 11 Issue: 1
Author(s): Dubravka Stanetic and Gerhard Buchbauer
Affiliation:
Keywords: Biological properties, biosynthesis, essential oils, volatile diterpenoids.
Abstract: The aim of this literature review is to investigate if volatile diterpenoids, a small group of compounds, found in some essential oils, have any of the various biological activities which are generally attributed to essential oils. The importance to emphasize is the fact, that in nature, the number of volatile and bio-active diterpenoids is very small. Different plant families have been investigated and their essential oils have been distilled, compounds were isolated and then analyzed. Almost all isolated diterpenoids showed to have cytotoxic, antioxidant or antimicrobial activities alone or more often in synergism with other essential oil compounds. For example labdane-type and abietane-type diterpenes have shown cytotoxicity against tumor cells and abietane-like compounds play an important role as antioxidants. For each isolated class of diterpenoids one or more biological activities can be observed.
Export Options
About this article
Cite this article as:
Stanetic Dubravka and Buchbauer Gerhard, Biological Activity of Some Volatile Diterpenoids, Current Bioactive Compounds 2015; 11 (1) . https://dx.doi.org/10.2174/157340721101150804150419
DOI https://dx.doi.org/10.2174/157340721101150804150419 |
Print ISSN 1573-4072 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6646 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Cannabinoid Modulation of Neuroinflammatory Disorders
Current Neuropharmacology Are Catechins, Polyphenols in Tea, Good for Your Health?
Current Nutrition & Food Science Neuroprotective Effects of Tetracyclines: Molecular Targets, Animal Models and Human Disease
CNS & Neurological Disorders - Drug Targets Mechanisms of Neuroprotection by Polyphenols
Current Medicinal Chemistry - Central Nervous System Agents Post-Transcriptional Regulation of HSP70 Expression Following Oxidative Stress in SH-SY5Y Cells: The Potential Involvement of the RNA-Binding Protein HuR
Current Pharmaceutical Design Glaucoma and Aging
Current Aging Science Targeting the Autophagy/Lysosomal Degradation Pathway in Parkinson´s Disease
Current Neuropharmacology Protective Effects of Caffeic Acid and the Alzheimer's Brain: An Update
Mini-Reviews in Medicinal Chemistry Role of Methylene Blue in Trauma Neuroprotection and Neuropsychiatric Diseases
CNS & Neurological Disorders - Drug Targets Contrasting Roles of the Galectin-3 in the Schizophrenia Onset, Clinical Presentation, and Somatic Comorbidity
Current Topics in Medicinal Chemistry Editorial (Thematic Issue: Linkage of Neurodegenerative Disorders with Other Health Issues – Volume I)
CNS & Neurological Disorders - Drug Targets Calpain Inhibition: A Therapeutic Strategy Targeting Multiple Disease States
Current Pharmaceutical Design Role of Metals in Neuronal Apoptosis: Challenges Associated with Neurodegeneration
Current Alzheimer Research Protein Kinase C-Related Kinase (PKN/PRK). Potential Key-Role for PKN1 in Protection of Hypoxic Neurons
Current Neuropharmacology Etiology of Neuroinflammatory Pathologies in Neurodegenerative Diseases: A Treatise
Current Psychopharmacology Dysregulation of RNA Mediated Gene Expression in Motor Neuron Diseases
CNS & Neurological Disorders - Drug Targets Amyloid-Related Biomarkers for Alzheimers Disease
Current Medicinal Chemistry Curcumin Exposure Modulates Multiple Pro-Apoptotic and Anti-Apoptotic Signaling Pathways to Antagonize Acetaminophen-Induced Toxicity
Current Neurovascular Research Matter of Life and Death: the Pharmacological Approaches Targeting Apoptosis in Brain Diseases
Current Pharmaceutical Design Pathogenic Mechanisms and Therapeutic Strategies in Spinobulbar Muscular Atrophy
CNS & Neurological Disorders - Drug Targets