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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Total Synthesis of Xestoaminol C from D-Glucose

Author(s): Hanmanth R. Vulupala, Yasodakrishna Sajja, Rajashaker Bantu and Lingaiah Nagarapu

Volume 19, Issue 20, 2015

Page: [2040 - 2045] Pages: 6

DOI: 10.2174/1385272819666150730214151

Price: $65

Abstract

A convenient and practical approach for the total synthesis of Xestoaminol C has been accomplished with 16.43% overall yield from commercially available D-glucose. The synthesis involves SN2 type centre inversion with azido group, Staudinger reaction, Wittig olefination and Pearlman’s catalytic hydrogenation.

Keywords: Staudinger reaction, Wittig olefination, oxidative cleavage, hydrogenation, D-glucose.

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