Abstract
An efficient, mild, cost effective and eco-friendly synthesis of 2,3- dihydroquinazoline- 4(1H)-ones is described in which isatoic anhydride, primary amines and variety of aldehydes react in the presence of citric acid as a green, bioorganic and inexpensive catalyst via rapid one-pot threecomponent reaction in boiling ethanol.
Keywords: Aldehydes, bioorganic catalyst, citric acid, 2, 3-dihydroquinazoline-4(1H)-ones, isatoic anhydride, multicomponent synthesis, primary amines.
Graphical Abstract
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
41