Abstract
An efficient and mild method for thioacetalization of 2-alkynylbenzaldehydes in the presence of a catalytic amount of silver triflate has been described. This reaction proceeded efficiently to generate 2-alkynylbenzaldehydes thioacetals in good to excellent yields at room temperature within short reaction time (no more than 30 min). This transformation was extremely easy to perform without the need of using anhydrous solvent and inert atmosphere. Chemoselective thioacetalization of benzaldehyde in the presence of acetophenone was also demonstrated.
Keywords: 2-Alkynylbenzaldehyde, Silver triflate, Thioacetalization, Thioacetal, Thiol.
Related Books
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
Advances in Organic Synthesis
35
5
1