Abstract
Every year, cancer takes the life of millions of people. Conventional treatments have produced unsatisfactory results for some types of cancer, and the side effects are extensive, leading to a shift in the focus of treatment towards alternative medicines. Indeed, medicinal plants have long been investigated by scientists for their anti-cancer properties. Some phytochemicals that are important active constituents of plants, including catechins, ursolic acid, silymarin, glycyrrhizin, ellagic acid, gallic acid and various types of flavonoids, have shown promise in future cancer management. The current review covers various aspects of cancer treatment based on medicinal plants at molecular level and sheds light on their structures and modes of action.
Keywords: Cancer treatment, phytochemicals, flavonoids, apoptosis.
Medicinal Chemistry
Title:Roles of Natural Compounds from Medicinal Plants in Cancer Treatment: Structure and Mode of Action at Molecular Level
Volume: 11 Issue: 7
Author(s): Mahmood Rasool, Arif Malik, Abdul Manan, Mahwish Arooj, Mahmood Husain Qazi, Mohammad Amjad Kamal, Ishfaq Ahmed Sheikh, Siew Hua Gan, Muhammad Asif and Muhammad Imran Naseer
Affiliation:
Keywords: Cancer treatment, phytochemicals, flavonoids, apoptosis.
Abstract: Every year, cancer takes the life of millions of people. Conventional treatments have produced unsatisfactory results for some types of cancer, and the side effects are extensive, leading to a shift in the focus of treatment towards alternative medicines. Indeed, medicinal plants have long been investigated by scientists for their anti-cancer properties. Some phytochemicals that are important active constituents of plants, including catechins, ursolic acid, silymarin, glycyrrhizin, ellagic acid, gallic acid and various types of flavonoids, have shown promise in future cancer management. The current review covers various aspects of cancer treatment based on medicinal plants at molecular level and sheds light on their structures and modes of action.
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Cite this article as:
Rasool Mahmood, Malik Arif, Manan Abdul, Arooj Mahwish, Qazi Husain Mahmood, Kamal Amjad Mohammad, Sheikh Ahmed Ishfaq, Gan Hua Siew, Asif Muhammad and Naseer Imran Muhammad, Roles of Natural Compounds from Medicinal Plants in Cancer Treatment: Structure and Mode of Action at Molecular Level, Medicinal Chemistry 2015; 11 (7) . https://dx.doi.org/10.2174/1573406411666150430120038
DOI https://dx.doi.org/10.2174/1573406411666150430120038 |
Print ISSN 1573-4064 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6638 |
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Carbohydrates in Computational and Medicinal Chemistry
Carbohydrates are the most essential organic molecules and are involved in the maintenance of various physiological and metabolic processes in living organisms. Carbohydrate-based compounds have come to the attention of researchers because of their significant contributions to biological functions, such as cell development and cell proliferation, connections between several cells, ...read more
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Scope of the Thematic Issue: Correlation between structure and function is one of the important aspects of the success of anti-cancer compounds associated with their structure-activity interactions, physiology, biochemical, molecular, and genetic processes. Overcoming these obstacles is key to obtaining further insights into developments in rational drug design, bioorganic chemistry, ...read more
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