Abstract
“There is a growing body of evidence suggesting that wound healing in chronic diabetic foot ulcers is growth factor dependent, and that the therapeutic delivery of these growth factors to wounds topically, has the potential ability to accelerate wound healing in conjunction with conventional wound care”. There is, however, confusion about the utility of platelet rich plasma because the studies that have evaluated them use a wide range of products (different platelet and leukocyte concentrations, different techniques and frequencies of application, very heterogeneous simple, and different endpoints) making almost impossible to compare data and draw conclusions. In this study, we have analyzed the different platelet rich plasma products from a new perspective: cost-efficiency. According to our data, we observe that platelet rich plasma is a cost-effective option that allows faster healing of ulcers, and that should be taken into account in patients with long evolution ulcers.
Keywords: Cost-benefit analysis, skin ulcers, platelet-rich plasma, varicose ulcers.
Current Pharmaceutical Biotechnology
Title:Effectiveness and Efficiency of Platelet Rich Plasma in the Treatment of Diabetic Ulcers
Volume: 16 Issue: 7
Author(s): Raquel Cobos, Felipe Aizpuru, Naiara Parraza, Eduardo Anitua and Gorka Orive
Affiliation:
Keywords: Cost-benefit analysis, skin ulcers, platelet-rich plasma, varicose ulcers.
Abstract: “There is a growing body of evidence suggesting that wound healing in chronic diabetic foot ulcers is growth factor dependent, and that the therapeutic delivery of these growth factors to wounds topically, has the potential ability to accelerate wound healing in conjunction with conventional wound care”. There is, however, confusion about the utility of platelet rich plasma because the studies that have evaluated them use a wide range of products (different platelet and leukocyte concentrations, different techniques and frequencies of application, very heterogeneous simple, and different endpoints) making almost impossible to compare data and draw conclusions. In this study, we have analyzed the different platelet rich plasma products from a new perspective: cost-efficiency. According to our data, we observe that platelet rich plasma is a cost-effective option that allows faster healing of ulcers, and that should be taken into account in patients with long evolution ulcers.
Export Options
About this article
Cite this article as:
Cobos Raquel, Aizpuru Felipe, Parraza Naiara, Anitua Eduardo and Orive Gorka, Effectiveness and Efficiency of Platelet Rich Plasma in the Treatment of Diabetic Ulcers, Current Pharmaceutical Biotechnology 2015; 16 (7) . https://dx.doi.org/10.2174/138920101607150427111926
DOI https://dx.doi.org/10.2174/138920101607150427111926 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
Call for Papers in Thematic Issues
Artificial Intelligence in Bioinformatics
Bioinformatics is an interdisciplinary field that analyzes and explores biological data. This field combines biology and information system. Artificial Intelligence (AI) has attracted great attention as it tries to replicate human intelligence. It has become common technology for analyzing and solving complex data and problems and encompasses sub-fields of machine ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
An Update on the Cardiovascular Effects of Quercetin, a Plant Flavonoid
Current Nutrition & Food Science Subject Index To Volume 4
Current HIV Research Cocaine Dependence and Stroke: Pathogenesis and Management
Current Neurovascular Research Role of Alpha-1 Antitrypsin (AAT) in Ocular Allergy and Uveitis
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Pharmacological Prolyl Hydroxylase Domain Inhibition as a Therapeutic Target for Parkinson’s Disease
CNS & Neurological Disorders - Drug Targets Editorial (Thematic Issue: Biologics in Autoimmune Diseases)
Current Pharmaceutical Biotechnology Inhibitors of Nitric Oxide Synthase: What's up and What's Next?
Current Enzyme Inhibition Cocaine and Acute Vascular Diseases
Current Drug Abuse Reviews Olanzapine-Induced Reversible Pellagroid Skin Lesion
Current Drug Safety Rituximab Therapy and Autoimmune Disease
Current Immunology Reviews (Discontinued) Urokinase-a Very Popular Cardiovascular Agent
Recent Patents on Cardiovascular Drug Discovery Radiopharmaceuticals in Neurological and Psychiatric Disorders
Current Clinical Pharmacology Inhibition of Smooth Muscle Cell Migration and Proliferation by Statins
Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) Editorial [Hot topic: Transportalopathy and Vascular Cell Dysfunction (Guest Editor: Luis Sobrevia)]
Current Vascular Pharmacology Covid-19 in Man: A Very Dangerous Affair
Endocrine, Metabolic & Immune Disorders - Drug Targets miR-27b-3p is Highly Expressed in Serum of Patients with Preeclampsia and has Clinical Significance
Endocrine, Metabolic & Immune Disorders - Drug Targets Schwann Cell Transplantation for CNS Repair
Current Medicinal Chemistry Pleural Involvement in Systemic Disorders
Current Drug Targets - Inflammation & Allergy Cell Cycle Arrest as a Therapeutic Target of Acute Kidney Injury
Current Protein & Peptide Science PPARγ Activation Improves the Molecular and Functional Components of Ito Remodeling by Angiotensin II
Current Pharmaceutical Design