Abstract
Montmorillonite K-10 clay has been identified as an efficient and green catalyst for the synthesis of 2-amino-4-aryl thiazole derivatives (3) in good to excellent isolated yields (80-96%) from α-brominated aralkyl ketones (1) and thiourea (2) in aqueous medium at 25-30°C. The present procedure offers advantages of short reaction time, simple work-up, high yields of products and the catalyst is environmentally benign and exhibits remarkable reusable activity by four times.
Keywords: Montmorillonite K-10 clay, phenacyl bromides, thiourea, water, 2-amino-4-aryl thiazoles.
Current Green Chemistry
Title:Montmorillonite K-10 Clay Mediated Green Synthesis of 2-Amino-4-aryl thiazole Derivatives from α-Brominated Aralkyl Ketones in Water
Volume: 2 Issue: 2
Author(s): Pinjari Md. K. Mohinuddin, Reddy B. Mohan, Sangita D. Kumar and Nallagondu C.G. Reddy
Affiliation:
Keywords: Montmorillonite K-10 clay, phenacyl bromides, thiourea, water, 2-amino-4-aryl thiazoles.
Abstract: Montmorillonite K-10 clay has been identified as an efficient and green catalyst for the synthesis of 2-amino-4-aryl thiazole derivatives (3) in good to excellent isolated yields (80-96%) from α-brominated aralkyl ketones (1) and thiourea (2) in aqueous medium at 25-30°C. The present procedure offers advantages of short reaction time, simple work-up, high yields of products and the catalyst is environmentally benign and exhibits remarkable reusable activity by four times.
Export Options
About this article
Cite this article as:
Mohinuddin Md. K. Pinjari, Mohan B. Reddy, Kumar D. Sangita and Reddy C.G. Nallagondu, Montmorillonite K-10 Clay Mediated Green Synthesis of 2-Amino-4-aryl thiazole Derivatives from α-Brominated Aralkyl Ketones in Water, Current Green Chemistry 2015; 2 (2) . https://dx.doi.org/10.2174/2213346102666150205100538
DOI https://dx.doi.org/10.2174/2213346102666150205100538 |
Print ISSN 2213-3461 |
Publisher Name Bentham Science Publisher |
Online ISSN 2213-347X |
Call for Papers in Thematic Issues
Green concepts' for modern organic synthesis
The 'green revolution', which is literally happening before our eyes and affects every aspect of life, also poses increasingly difficult challenges in the field of chemical synthesis. New solutions and ideas aimed at environmental protection while taking into account the principles of sustainable development are still desired. In this context, ...read more
Green Thermochemical Processes for Hydrogen Production: Circular Economy Approach
The Special Issue ?Green Thermochemical Processes for Hydrogen Production: Circular Economy Approach? welcomes research, review and mini-review papers focusing on the study and development of thermochemical processes for the valorization of byproducts, wastes, wastewaters and biomass to Hydrogen in a green and sustainable way. Processes driven by the supply from ...read more
Recent Advances on Green Catalysis and Drug Discovery
To save our loving ?Mother Nature? from the ever increasing chemical pollution scientists are continuously modifying their chemical processes to make them sustainable. As a result, last decade has shown a tremendous outburst in modifying organic transformations by following green credentials. Catalysts play an important role in organic transformations. Involvement ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Antisense Oligonucleotides in the Treatment of Cerebral Gliomas. Review of Concerning Patents
Recent Patents on CNS Drug Discovery (Discontinued) Application of Kinase Inhibitors for Anti-aging Intervention
Current Pharmaceutical Design Salivary Genomics, Transcriptomics and Proteomics: The Emerging Concept of the Oral Ecosystem and their Use in the Early Diagnosis of Cancer and other Diseases
Current Genomics Targeting Xanthine Oxidase by Natural Products as a Therapeutic Approach for Mental Disorders
Current Pharmaceutical Design Traumatic Spinal Cord Injury Alters Angiogenic Factors and TGF-Beta1 that may Affect Vascular Recovery
Current Neurovascular Research The Cardiac Microvasculature in Hypertension, Cardiac Hypertrophy and Diastolic Heart Failure
Current Vascular Pharmacology A Systems Biology Approach for miRNA-mRNA Expression Patterns Analysis in Rheumatoid Arthritis
Combinatorial Chemistry & High Throughput Screening Can Increased Food Intake Improve Psychosis? A Brief Review and Hypothesis
Current Molecular Pharmacology Etanercept for the Treatment of Dermatological Diseases
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry MicroRNA Pathways: An Emerging Role in Identification of Therapeutic Strategies
Current Gene Therapy Bioactive Fish Fatty Acids: Health Effects and Their Use as Functional Food Ingredients
Current Nutrition & Food Science Immunotoxin Lesion of the Cholinergic Nucleus Basalis Causes Aβ Deposition: Towards a Physiologic Animal Model of Alzheimers Disease
Current Medicinal Chemistry - Immunology, Endocrine & Metabolic Agents Polyphenols: Potential Future Arsenals in the Treatment of Diabetes
Current Pharmaceutical Design Computational Studies on the Prion Protein
Current Topics in Medicinal Chemistry Hematopoietic Stem Cells Therapies
Current Stem Cell Research & Therapy Dynamics of Diabetes and Obesity: An Alarming Situation in the Developing Countries in Asia
Mini-Reviews in Medicinal Chemistry Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment
Current Alzheimer Research Imaging Techniques as an Aid in the Early Detection of Cardiac Amyloidosis
Current Pharmaceutical Design Non-Analgesic Effects of Opioids: Opioids and the Endocrine System
Current Pharmaceutical Design Information-Theoretic Characterization of Brain Registration and Structure- Function Relationships
Neuroscience and Biomedical Engineering (Discontinued)