Generic placeholder image

Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Strategies and Methods for the Synthesis of Anticancer Natural Product Neopeltolide and its Analogs

Author(s): Yu Bai and Mingji Dai

Volume 19, Issue 10, 2015

Page: [871 - 885] Pages: 15

DOI: 10.2174/1385272819666150119225149

Price: $65

Abstract

Neopeltolide, isolated in 2007, with its novel structural features and potent anti-cancer cell proliferation activity, has attracted a tremendous amount of synthetic efforts. This review briefly and chronologically summarizes each synthesis with the main focus on the strategies and methodologies for the construction of its cistetrahydropyran- containing macrolactone core.

Keywords: Anticancer, carbonylation, macrolactone, neopeltolide, palladium, tetrahydropyran.

Graphical Abstract

Rights & Permissions Print Cite
© 2024 Bentham Science Publishers | Privacy Policy