Abstract
Diabetes mellitus (DM), an increasing health problem worldwide, is associated with severe cardiovascular complications. To date, the beneficial effects of physical activity in both prevention and treatment of DM and its complications are well established. Nevertheless, it appears that exercise training, depending on the load, exerts differential effects on the myocardium. Hence, in this review, the impact of exercise training, focusing on exercise modalities and adaptations in response to load, on diabetic cardiovascular function, are discussed. Molecular mechanisms that may be involved in these adaptions to exercise training are also addressed.
Keywords: Cardiac function, diabetes, exercise load, physical activity, molecular mechanisms.
Current Diabetes Reviews
Title:Physical Activity and Diabetic Cardiomyopathy: Myocardial Adaptation Depending on Exercise Load
Volume: 10 Issue: 6
Author(s): Solene Le Douairon Lahaye, Francoise Rannou Bekono and Tom Broderick
Affiliation:
Keywords: Cardiac function, diabetes, exercise load, physical activity, molecular mechanisms.
Abstract: Diabetes mellitus (DM), an increasing health problem worldwide, is associated with severe cardiovascular complications. To date, the beneficial effects of physical activity in both prevention and treatment of DM and its complications are well established. Nevertheless, it appears that exercise training, depending on the load, exerts differential effects on the myocardium. Hence, in this review, the impact of exercise training, focusing on exercise modalities and adaptations in response to load, on diabetic cardiovascular function, are discussed. Molecular mechanisms that may be involved in these adaptions to exercise training are also addressed.
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Cite this article as:
Lahaye Douairon Solene Le, Bekono Rannou Francoise and Broderick Tom, Physical Activity and Diabetic Cardiomyopathy: Myocardial Adaptation Depending on Exercise Load, Current Diabetes Reviews 2014; 10 (6) . https://dx.doi.org/10.2174/1573399811666141229151421
DOI https://dx.doi.org/10.2174/1573399811666141229151421 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
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