Abstract
The importance of diaminomaleonitrile (DAMN) as a readily available and cheap building block for the synthesis of various nitrogen heterocycles has attracted the attention of organic chemists worldwide. An enormous number of research studies have focused on the preparation of various heterocycles that play a role in the pharmaceutical, cosmetics, dyes, and pigment industries, among others. This review details developments in the chemistry and reactions of DAMN over the last decade including novel methods utilised, new compounds prepared, and significant applications.
Keywords: Diaminomaleonitrile, diazotization, imidazoles, N-heterocycles, pyrimidines, triazoles.
Current Organic Synthesis
Title:Recent Developments in the Chemistry of Diaminomaleonitrile
Volume: 12 Issue: 2
Author(s): Amal Al-Azmi
Affiliation:
Keywords: Diaminomaleonitrile, diazotization, imidazoles, N-heterocycles, pyrimidines, triazoles.
Abstract: The importance of diaminomaleonitrile (DAMN) as a readily available and cheap building block for the synthesis of various nitrogen heterocycles has attracted the attention of organic chemists worldwide. An enormous number of research studies have focused on the preparation of various heterocycles that play a role in the pharmaceutical, cosmetics, dyes, and pigment industries, among others. This review details developments in the chemistry and reactions of DAMN over the last decade including novel methods utilised, new compounds prepared, and significant applications.
Export Options
About this article
Cite this article as:
Al-Azmi Amal, Recent Developments in the Chemistry of Diaminomaleonitrile, Current Organic Synthesis 2015; 12 (2) . https://dx.doi.org/10.2174/1570179412666141226190750
DOI https://dx.doi.org/10.2174/1570179412666141226190750 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Kinase Chemogenomics: Targeting the Human Kinome for Target Validation and Drug Discovery
Mini-Reviews in Medicinal Chemistry COVID-19-associated Coagulopathy: Role of Vitamins D and K
Current Pharmaceutical Biotechnology COVID-19, SARS -CoV-2, Origin, Transmission and Treatment Aspects, A Brief Review
Infectious Disorders - Drug Targets Comparing India's Second COVID Wave with the First Wave-A Single-Center Experience
Recent Advances in Anti-Infective Drug Discovery Preface
Current Stem Cell Research & Therapy Thwarting Coronavirus Infections by Tapping Host Targets: The ‘Greek Gift Sacrifice’ to Curb the Menace of Drug Resistances
Current Molecular Pharmacology Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors as Therapeutics: Rationales, Controversies, Clinical Experience
Current Drug Targets Zinc Oxide Nanoparticles as a Potential Agent for Antiviral Drug Delivery Development: A Systematic Literature Review
Current Nanoscience Structure-Activity Relationships of Pyrrole Hydrazones as New Anti-Tuberculosis Agents
Medicinal Chemistry Therapy Stratifications and Novel Approach in Pursuit of Aids Related Kaposi’s Sarcoma Management- A paradigm for Non Invasiveness
Current Drug Delivery Recent Advances in N-Heterocycles for COVID-19 Treatment - A Mini Review
Medicinal Chemistry The Power of Enzyme Kinetics in the Drug Development Process
Current Pharmaceutical Biotechnology Modern Drug Discovery Technologies: Opportunities and Challenges in Lead Discovery
Combinatorial Chemistry & High Throughput Screening Adult Neurogenesis: Can Analysis of Cell Cycle Proteins Move Us “Beyond BrdU”?
Current Pharmaceutical Biotechnology Thiourea and Guanidine Derivatives as Antimalarial and Antimicrobial Agents<sup>§</sup>
Current Topics in Medicinal Chemistry Fusion Protein Targeted Antiviral Peptides: Fragment-Based Drug Design (FBDD) Guided Rational Design of Dipeptides Against SARS-CoV-2
Current Protein & Peptide Science Brain-Skin Connection: Stress, Inflammation and Skin Aging
Inflammation & Allergy - Drug Targets (Discontinued) Perspectives for the Use of N-acetylcysteine as a Candidate Drug to Treat COVID-19
Mini-Reviews in Medicinal Chemistry Pharmacological Exploration of Triazole-based Therapeutics for Alzheimer’s Disease: An Overview
Current Drug Targets Natural Product Inhibitors of Hsp90: Potential Leads for Drug Discovery
Mini-Reviews in Medicinal Chemistry