Abstract
Clinical trials demonstrated that statin therapy is associated with a significant reduction in cardiovascular morbidity and mortality when used for either primary or secondary prevention of cardiovascular events. Several studies have shown that statins, having an important effect in the prevention of acute coronary syndromes, are also able to prevent heart failure (HF) in patients with coronary artery disease. This review summarizes the experimental and clinical evidence regarding the role of statins in the management of HF.
Keywords: Statins, heart failure.
Current Vascular Pharmacology
Title:Pleiotropic Effects of Statin in Therapy in Heart Failure: A Review
Volume: 12 Issue: 6
Author(s): Michele Correale, Silvia Abruzzese, Carmen A. Greco, Morena Concilio, Matteo Di Biase and Natale D. Brunetti
Affiliation:
Keywords: Statins, heart failure.
Abstract: Clinical trials demonstrated that statin therapy is associated with a significant reduction in cardiovascular morbidity and mortality when used for either primary or secondary prevention of cardiovascular events. Several studies have shown that statins, having an important effect in the prevention of acute coronary syndromes, are also able to prevent heart failure (HF) in patients with coronary artery disease. This review summarizes the experimental and clinical evidence regarding the role of statins in the management of HF.
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Cite this article as:
Correale Michele, Abruzzese Silvia, Greco A. Carmen, Concilio Morena, Biase Di Matteo and Brunetti D. Natale, Pleiotropic Effects of Statin in Therapy in Heart Failure: A Review, Current Vascular Pharmacology 2014; 12 (6) . https://dx.doi.org/10.2174/1570161112999141127161508
DOI https://dx.doi.org/10.2174/1570161112999141127161508 |
Print ISSN 1570-1611 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6212 |
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